Screening of some Indian medicinal plants for their antimicrobial properties

Ahmad, Iqbal; Mehmood, Zafar; Mohammad, Faiz

doi:10.1016/s0378-8741(98)00055-5

Cited by 695 publications

(429 citation statements)

References 8 publications

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“…Found that the antifungal active principal is a phenolic compound. Methanol extract of A. procera showed antifungal activity against seven fungal strains and ethyl acetate extracts showed activity against any five fungi [11] In addition these results confirmed the evidence in previous studies reported that the methanol is a better solvent for more constituent extraction of antimicrobial substance from medicinal plants compared to other solvents such as water, ethanol and hexane [12,[13][14]. The antimicrobial activity of D. hamiltonii against human pathogenic bacteria and food borne fungi has been demonstrated by [15] …”

Section: Discussionsupporting

confidence: 75%

Antimicrobial Activity of Methanolic Root Extract of <i>Decalepis hamiltonii </i>Wight & Arn

Prakash

Manivasagaperumal

2016

ILNS

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ABSTRACT:The present study was quantitative analysis and antimicrobial activity of petroleum ether, chloroform, ethyl acetate, methanol root extracts. The gram positive and gram negative bacterial and fungal species by the disc diffusion method at various concentration (250µl-1000µl).The results was present in the phenolic and flavonoid content compared to extracts. All the root extract against to Bacillus subtilis and Streptococcus pyogenes and fungal species Candida albicans at highest inhibition at concentration of methanolic root extract of zone formation. The preliminary studies on Decalepis hamiltonii root extract exhibited their antimicrobial potential which could be exploited further and future pharmaceutical, therapeutic efficiency and food preservation and applications

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Section: Discussionsupporting

confidence: 75%

Antimicrobial Activity of Methanolic Root Extract of <i>Decalepis hamiltonii </i>Wight & Arn

Prakash

Manivasagaperumal

2016

ILNS

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“…The precipitated solid was recrystallized from appropriate solvent to afford the desired compound . N,N'-(5,5'-(6,6'-(2-(1,3-Bis(2-(5-acetamido-3-acetyl-2,3-dihydro-1,3,4-thiadiazol-2-yl) 5'-(4,4'-(2,3-Bis((4-(3-acetyl-5-(N-methylacetamido)-2,3-dihydro-1,3,4-thiadiazol-2-yl)-2-methoxyphenoxy)methyl)but-2-ene-1,4-diyl)bis(oxy)bis(3-methoxy-4,1-phenylene))bis(4-acetyl-4,5-dihydro-1,3,4-thiadiazole-5,2-diyl) Simple susceptibility screening test using agar-well diffusion method 63 as adapted earlier 64 was used. Each microorganism was suspended in Mueller Hinton (MH) (Difco, Detroit, MI) broth and diluted approximately 10 6 colony forming unit (cfu) per ml.…”

Section: General Methods For the Synthesis Tetra-4-methyl-5-ethoxy Carmentioning

confidence: 99%

Synthesis and characterizations of some new tetra thiosemicarbazones and their cyclization reactions; tetra 4-methyl-5-etoxycarbonyl-2,3-dihydro-1,3-thiazole and tetra 2-acetylamino-4-acetyl-4,5-dihydro-1,3,4-thiodiazole derivatives

Er¹,

Ünver²,

Sancak³

et al. 2008

Arkivoc

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Tetra-aldehyde and ketone derivatives (2a-d) which were used to obtain tetra thiosemicarbazone compounds 3a-h were synthesized via the reaction of Ethene-1,1,2,2,-tetra-yl-tetra-methylenetetra-bromide (1) with aldehydes and ketons. Then, tetra-thiosemicarbazone compounds 3a-h were obtained from the reactions of tetra-aldehyde and keton derivatives (2a-d) with thiosemicarbazite and 4-methyl thiosemicarbazite, respectively. In the same way, tetra-4-methyl-5-ethoxycarbonyl-2,3-dihydro-1,3-thiazole compounds 4a-h were synthesized via the reaction of tetra-thiosemicarbazone compounds 3a-h with ethyl-2-chloroacetoacetate. Then, tetrathiosemicarbazone compounds 3a-h were reacted with acetic anhydride, and yielded tetra-2-acetyl-amino-4-acetyl-4,5-dihydro-1,3,4-thiodiazol compounds (5a,b,c,e,f,g). They were characterized by elemental analysis, infrared, 1 H and 13 C-NMR, mass spectroscopy. Then, the microbial features of all compounds were studied by the known method.

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“…Antibacterial activity of different extracts was determined by agar well-diffusion method (Ahmad et al, 1998). In vitro antibacterial activity was screened by using Mueller-Hinton Agar (MHA) medium no.…”

Section: Antibacterial Testingmentioning

confidence: 99%

Antimicrobial efficacy of Althaea officinalis Linn. seed extracts and essential oil against respiratory tract pathogens

Gautam¹,

Bithel²,

Kumar³

et al. 2015

J App Pharm Sci

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In present study, Althaea officinalis seed extracts and essential oil were screened for antimicrobial activity against five bacteria and one fungi responsible for dominant, lethal or opportunistic infection of respiratory regions. The maximum inhibition was noted by essential oil against Streptococcus pyogenes (21.3±0.28 mm) and Haemophilus influenzae (19.0±0.50 mm) at 200 mg/ml. The minimum inhibitory concentration values for methanol extract was 3.12-12.5 mg/ml. The antifungal activity noted highest with 41.28% by essential oil and 36.27% inhibition by aqueous extract represented by dosage-response curve. Key words:Althaea officinalis, antimicrobial, dosageresponse curve, minimum inhibitory concentration, respiratory tract infections INTRODUCTIONPlants are the pavement bricks of all the living organisms on the earth. They produce a wide range of secondary metabolites such as alkaloids, unsaturated fatty acids, flavonoids, phenols, tannins and terpenes that can be used to treat various chronic and infectious diseases (Reichling, 2010). In recent years, increasing strains of microorganisms throughout the world have developed resistance to large number of antibiotics that has created immense clinical problem and made the management of infectious diseases quite complicated (Davis, 1994). The way to avoid antibiotic resistance of pathogenic species is by using plant based compounds rather than existing synthetic antimicrobial agents (Shah, 2005). Althaea officinalis Linn. (Malvaceae) is commonly known as Khatmi in Hindi and Marshmallow in English. It is native of British Isles and found in temperate regions of India, currently it is distributed throughout Europe and some parts of America (Ross, 2001). A. officinalis is a perennial herb 60-120 cm high. Stem is erect, woody and unbranched. Leaves are short-petioled with an ovate and acute leaf blade. Shiv Shanker Gautam, Department of Botany and Microbiology, Gurukul Kangri University, Haridwar-249404, Uttarakhand, India mail id: gautam12shiv@gmail.com The reddish-white flowers are usually in axillary or terminal cluster. Compressed dark brown kidney-shaped seeds are glabrous (Ozkan and Uzunhisarcikli, 2009). A. officinalis is used in irritation of oral, pharyngeal mucosa and associated dry cough, mild gastritis, skin burns, insect bites, catarrh of the mouth, throat, gastrointestinal tract and urinary tract, inflammation, ulcers, abscesses, burns, constipation and diarrhoea. Seeds are diuretic and febrifuge (Shah, 2011). * Corresponding AuthorIt has been used as an aid in promoting coughing up of phlegm and respiratory problems. Due to high contents of polysaccharides, it is used in relieving dryness and chest and throat irritation happened by colds and persistent coughing (Sutovska et al., 2007). A. officinalis has a broader spectrum of antibacterial as well as antifungal activity. The antibacterial activity of A. officinalis roots were tested against anaerobic and facultative aerobic periodontal bacteria (Lauk et al., 2003). Many researches showed that A. off...

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Screening of some Indian medicinal plants for their antimicrobial properties

Cited by 695 publications

References 8 publications

Antimicrobial Activity of Methanolic Root Extract of <i>Decalepis hamiltonii </i>Wight & Arn

Antimicrobial Activity of Methanolic Root Extract of <i>Decalepis hamiltonii </i>Wight & Arn

Synthesis and characterizations of some new tetra thiosemicarbazones and their cyclization reactions; tetra 4-methyl-5-etoxycarbonyl-2,3-dihydro-1,3-thiazole and tetra 2-acetylamino-4-acetyl-4,5-dihydro-1,3,4-thiodiazole derivatives

Antimicrobial efficacy of Althaea officinalis Linn. seed extracts and essential oil against respiratory tract pathogens

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Screening of some Indian medicinal plants for their antimicrobial properties

Cited by 695 publications

References 8 publications

Antimicrobial Activity of Methanolic Root Extract of <i>Decalepis hamiltonii </i>Wight &amp; Arn

Antimicrobial Activity of Methanolic Root Extract of <i>Decalepis hamiltonii </i>Wight &amp; Arn

Synthesis and characterizations of some new tetra thiosemicarbazones and their cyclization reactions; tetra 4-methyl-5-etoxycarbonyl-2,3-dihydro-1,3-thiazole and tetra 2-acetylamino-4-acetyl-4,5-dihydro-1,3,4-thiodiazole derivatives

Antimicrobial efficacy of Althaea officinalis Linn. seed extracts and essential oil against respiratory tract pathogens

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Antimicrobial Activity of Methanolic Root Extract of <i>Decalepis hamiltonii </i>Wight & Arn

Antimicrobial Activity of Methanolic Root Extract of <i>Decalepis hamiltonii </i>Wight & Arn