Screening of plant toxins in food, feed and botanicals using full-scan high-resolution (Orbitrap) mass spectrometry

Mol, Hans; Dam, R.C.J. van; Zomer, Paul; Mulder, Patrick P.J.

doi:10.1080/19440049.2011.603704

Cited by 83 publications

(39 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The reason for using this procedure instead of a simpler extraction without the partition step was its discrimination of co-extractants in the final extract. Because the QuEChERS procedure was previously used for qualitative screening analysis of AA and other plant toxins in various complex matrices (Mol et al 2011), we expected that this extraction approach could also be successfully used in a quantitative application. The extraction was optimised based on evaluation of peak areas obtained by analysis of extracts of a single herb powder containing AA (product 7; Table 1).…”

Section: Extraction Proceduresmentioning

confidence: 99%

Quantification of aristolochic acids I and II in herbal dietary supplements by ultra-high-performance liquid chromatography–multistage fragmentation mass spectrometry

Václavík¹,

Krynitsky²,

Rader³

2014

Food Additives & Contaminants: Part A

View full text Add to dashboard Cite

A rapid, selective and sensitive ultra-high-performance liquid chromatography-multistage fragmentation mass spectrometry (UHPLC-MS³) method was developed and evaluated for the determination of aristolochic acids I and II (AA I and II) in herbal dietary supplements. A hybrid triple quadrupole/linear ion-trap mass spectrometry was used to monitor MS³ ion transitions m/z 359.2 > 298.1 > 268.0 and m/z 329.2 > 268.2 > 238.0 to detect AA I and II, respectively. The extraction and clean-up of target analytes from dry powdered samples was performed using the quick, easy, cheap, effective, rugged and safe (QuEChERS) procedure. Herbal liquid extracts were analysed directly. Average recoveries ranged from 89% to 112%, with relative standard deviations (RSDs) ranging from 3% to 16%. Limits of quantification (LOQs) estimated for three selected matrices were as follows (AA I/II): 5/10 ng g⁻¹ (tablets); 25/50 ng g⁻¹ (capsules); and 2.5/5.0 ng ml⁻¹ (liquid herbal extract). The method was applied in a limited survey of 30 herbal products marketed in the United States via the Internet. AA I and II were detected in 20% and 7%, respectively, of tested samples.

show abstract

Section: Extraction Proceduresmentioning

confidence: 99%

Quantification of aristolochic acids I and II in herbal dietary supplements by ultra-high-performance liquid chromatography–multistage fragmentation mass spectrometry

Václavík¹,

Krynitsky²,

Rader³

2014

Food Additives & Contaminants: Part A

View full text Add to dashboard Cite

show abstract

“…Due to its dynamicity and simplicity this method can be applied to the analysis of other contaminants and residues, such as mycotoxins (Zachariasova et al, 2010), steroids (Klinsunthorn, Petsom, & Nhujak, 2011) and PAs (Kempf et al, 2011;Mol et al, 2011) in many different matrices.…”

Section: Introductionmentioning

confidence: 99%

UPLC–MS/MS method for determination of selected pyrrolizidine alkaloids in feed

et al. 2015

View full text Add to dashboard Cite

“…Table 1 summarises the exact masses and characteristic fragments used respectively for quantification and confirmation of the target compounds. Limits of detection (LODs) and of quantitation (LOQs) were established according to Mol et al (2011) and Eurachem (1993) respectively. Method accuracy was estimated in terms of mean relative recovery by spiking 8 natural samples with 1000 lg/L of each phenol.…”

Section: Simple Phenolic Characterisation Of Winementioning

confidence: 99%

The impact of different barrel sanitation approaches on the spoilage microflora and phenols composition of wine

et al. 2017

View full text Add to dashboard Cite

Careful control of spoilage microflora inside wine containers is a key issue during winemaking. To date, attention has been paid to the development of an effective protocol for the eradication of spoilage agents, especially Brettanomyces, from barrels. Few studies have taken into account the modifications caused by sanitation treatments in wine and wood barrels. In the present study the effects of two sanitation treatments (ozone and sodium hydroxide) on barrel spoilage microflora and the composition of the wine stored inside them were evaluated. The phenols of wine (38 compounds) were characterised using a UHPLC-MS during the first 3 months of wine ageing, to see possible alterations in composition due to the chemical exchange from wood to wine in presence of sanitising agents. With the same scope, a panel of 13 judges carried out sensorial analysis of wines. The results showed that the tested treatments had little effect on the organoleptic characteristics of wines, but underline the different performance of the sanitation treatments in terms of eradicating microorganisms.

show abstract

Screening of plant toxins in food, feed and botanicals using full-scan high-resolution (Orbitrap) mass spectrometry

Abstract: . Screening of plant toxins in food, feed and botanicals using full scan high resolution (Orbitrap) mass spectrometry. Food Additives and Contaminants, 2011, 28 (10), pp.1405-1423. <10.1080/19440049.2011

Cited by 83 publications

References 36 publications

Quantification of aristolochic acids I and II in herbal dietary supplements by ultra-high-performance liquid chromatography–multistage fragmentation mass spectrometry

Quantification of aristolochic acids I and II in herbal dietary supplements by ultra-high-performance liquid chromatography–multistage fragmentation mass spectrometry

UPLC–MS/MS method for determination of selected pyrrolizidine alkaloids in feed

The impact of different barrel sanitation approaches on the spoilage microflora and phenols composition of wine

Contact Info

Product

Resources

About