Screening of medicinal plants from Trinidad and Tobago for antimicrobial and insecticidal properties

Chariandy, C.M; Seaforth, C. E.; Phelps, Robert A.; Pollard, G. V.; Khambay, B. P. S.

doi:10.1016/s0378-8741(98)00130-5

Cited by 119 publications

(70 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…1 For thousands of years, traditional plant derived medicines have been used in most parts of the world and their use in fighting microbial disease is becoming the focus of intense study. 2,3 Whilst much of the research into traditional medicinal plant use has focused on Asian, 4 African 5 and South American 6 plants, the therapeutic potential of the flora of Australia has been recognised for many thousands of years. The first Australians had well developed ethno-pharmacological systems and understood the therapeutic properties of a wide variety of aromatic Australian plants.…”

Section: Introductionmentioning

confidence: 99%

Cinnamomum Oliveri F. M. Bailey Leaf Solvent Extractions Inhibit the Growth of a Panel of Pathogenic Bacteria

Chikowe¹,

Mpala²,

Cock³

2017

View full text Add to dashboard Cite

Introduction: Cinnamomum oliveri F. M. Bailey is a rain forest tree native to Australia. Decoctions, infusions and essential oils produced from the leaves were used traditionally to treat a variety of bacterial diseases. Despite this, C. oliveri leaf extractions have not been rigorously examined for antibacterial properties against many pathogens. Methods: The antimicrobial activity of C. oliveri leaf extractions was investigated by disc diffusion and growth time course assays against a panel of pathogenic bacteria. The growth inhibitory activity was quantified by MIC determination. Toxicity was determined using the Artemia franciscana nauplii bioassay. Results: C. oliveri leaf solvent extractions inhibited the growth of a wide range of bacterial species. Growth of both gram positive and gram negative bacteria was inhibited by the C. oliveri leaf extracts to approximately the same extent. The methanolic extracts were generally most potent growth inhibitors. The methanolic, aqueous and ethyl acetate C. oliveri leaf extracts were particularly potent inhibitors of P. mirabilis growth, with MIC values as low as 127 µg/mL (methanolic extract). A. coli, K. pneumoniae and B. cereus were also particularly susceptible to the methanolic, aqueous and ethyl acetate extracts, with MIC values generally substantially <1000 µg/ mL. The antibacterial activity of the methanolic C. oliveri leaf extract was further investigated by growth time course assays which showed significant growth inhibition in cultures of E. coli, K. pneumoniae and P. mirabilis within 1 h of exposure. All extracts were determined to be nontoxic in the Artemia franciscana nauplii bioassay, indicating their safety for internal use as well as for topical uses. Conclusions: The lack of toxicity of the C. oliveri leaf extracts and their growth inhibitory bioactivity against a panel of pathogenic bacteria partially validate the traditional usage of these species to treat bacterial diseases and indicate their potential in the development of antiseptic agents.

show abstract

Section: Introductionmentioning

confidence: 99%

Cinnamomum Oliveri F. M. Bailey Leaf Solvent Extractions Inhibit the Growth of a Panel of Pathogenic Bacteria

Chikowe¹,

Mpala²,

Cock³

2017

View full text Add to dashboard Cite

show abstract

“…Additionally, J. gossypiifolia L. and J. dioica Sessé ex Cerv. showed antibacterial activity (Chariandy et al, 1999), and the methanol extract of the leaves of Jatropha gaumeri Greenm. showed significant antioxidant activity (Can-Ake et al, 2004).…”

Section: Introductionmentioning

confidence: 99%

Biological Properties and Chemical Composition of Jatropha Neopauciflora Pax

Hernández-Hernández¹,

Alarcón-Aguilar²,

Jiménez-Estrada³

et al. 2016

AJTCAM

View full text Add to dashboard Cite

Background: Ethnopharmacological relevance. Jatropha neopauciflora (Pax) is an endemic species of the TehuacanCuicatlan Valley, Mexico. This species has long been used as a remedy to alleviate illnesses of bacterial, fungal and viral origin. Aim of the study. Experimentally test the traditional use of Jatropha neopauciflora in Mexican traditional medicine. Materials and methods. The methanol extract (MeOH1), of Jatropha neopauciflora (Euphorbiaceae) was obtained by maceration. Next, the methanol (MeOH2) and hexane (H) fractions were obtained. The essential oil was obtained by hydrodistillation. The extract, fractions and essential oil were analyzed by GC-MS. The antimicrobial activity was measured by the disc diffusion agar and radial inhibition growth methods. Results: The extract and fractions showed antibacterial activity against eleven strains (five Gram-positive and six Gramnegative) and a bacteriostatic effect in the survival curves for Staphylococcus aureus and Vibrio cholerae. The extract and fractions were also shown to have antifungal activity, particularly against Trichophyton mentagrophytes (CF 50 = MeOH1: 1.07 mg/mL, MeOH2: 1.32 mg/mL and H: 1.08 mg/mL). The antioxidant activity of MeOH1 (68.6 g/mL) was higher than for MeOH2 (108.1 g/mL). The main compounds of the essential oil were -pinene, 1,3,8-p-menthatriene, ledene, mmenthane, linalyl acetate and 3-carene. The main compounds of MeOH1 were β-sitosterol, lupeol and pyrogallol; the main compounds of MeOH2 were β-sitosterol, spathulenol, coniferyl alcohol and lupeol; and the main compounds of H were β-sitostenone, -sitosterol and stigmasterol. Conclusions: This study indicates that Jatropha neopauciflora is a potential antibacterial and antifungal agent.

show abstract

“…Traditional plant derived medicines have been used in most parts of the world and their use in combating microbial disease is becoming the focus of several studies (Bhavnani and Ballow, 2000;Chariandy et al, 1999). Plant derived substances have recently become of great interest owing to their resourceful applications.…”

Section: Introductionmentioning

confidence: 99%

Screening of Antimicrobial Potential of Barleria prionitis Linn Aerial Parts against Common Respiratory Tract Pathogens

Singh¹,

Pathak²,

neet³

2016

Int.J.Curr.Microbiol.App.Sci

View full text Add to dashboard Cite

Screening of medicinal plants from Trinidad and Tobago for antimicrobial and insecticidal properties

Cited by 119 publications

References 7 publications

Cinnamomum Oliveri F. M. Bailey Leaf Solvent Extractions Inhibit the Growth of a Panel of Pathogenic Bacteria

Cinnamomum Oliveri F. M. Bailey Leaf Solvent Extractions Inhibit the Growth of a Panel of Pathogenic Bacteria

Biological Properties and Chemical Composition of Jatropha Neopauciflora Pax

Screening of Antimicrobial Potential of Barleria prionitis Linn Aerial Parts against Common Respiratory Tract Pathogens

Contact Info

Product

Resources

About