Screening of Forestry Workers in Guadalajara Province (Spain) for Antibodies to Lymphocytic Choriomeningitis Virus, Hantavirus, Rickettsia spp. and Borrelia burgdorferi

Lledó, Lourdes; Giménez-Pardo, Consuelo; Gegúndez, María Isabel

doi:10.3390/ijerph16224500

Cited by 9 publications

(11 citation statements)

References 37 publications

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“…After applying the inclusion and exclusion criteria (Figure 1), a total of 42 articles were included in the analyses and summarized, with a total of 28 estimates on agricultural workers and 22 on forestry workers, from 20 studies reporting on agricultural workers , 14 on forestry workers [39][40][41][42][43][44][45][46][47][48], and eight further studies reporting on both occupational groups [15,18,[21][22][23]49]. In one of the earlier studies, authors reported agricultural and forestry workers as a single exposure group, and the estimates were therefore included in both sub-analyses [30].…”

Section: Resultsmentioning

confidence: 99%

“…Estimates on forestry workers were available only from European [15,[21][22][23]30,[40][41][42][43][44][45][46][47]49,55,[57][58][59][60] and American regions [18,48]. Two of the European reports [45,59] seemly reported on the same occupational groups (i.e., forestry workers from Poland), focusing either on PUUV [45] or DOBV [59] but no specific disclosure was provided by study authors.…”

Section: Studies On Forestry Workersmentioning

confidence: 99%

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Occupational Hantavirus Infections in Agricultural and Forestry Workers: A Systematic Review and Metanalysis

Riccò

Peruzzi

Ranzieri

et al. 2021

Viruses

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Hantaviruses are zoonotic pathogens that can cause serious human disorders, including hemorrhagic fever with renal syndrome and hantavirus cardiopulmonary syndrome. As the main risk factor for human infections is the interaction with rodents, occupational groups such as farmers and forestry workers are reportedly at high risk, but no summary evidence has been collected to date. Therefore, we searched two different databases (PubMed and EMBASE), focusing on studies reporting the prevalence of hantaviruses in farmers and forestry workers. Data were extracted using a standardized assessment form, and results of such analyses were systematically reported, summarized and compared. We identified a total of 42 articles, including a total of 28 estimates on farmers, and 22 on forestry workers, with a total workforce of 15,043 cases (821 positive cases, 5.5%). A pooled seroprevalence of 3.7% (95% confidence interval [95% CI] 2.2–6.2) was identified in farmers, compared to 3.8% (95% CI 2.6–5.7) in forestry workers. Compared to the reference population, an increased occurrence was reported for both occupational groups (odds ratio [OR] 1.875, 95% CI 1.438–2.445 and OR 2.892, 95% CI 2.079–4.023 for farmers and forestry workers, respectively). In summary, our analyses stress the actual occurrence of hantaviruses in selected occupational groups. Improved understanding of appropriate preventive measures, as well as further studies on hantavirus infection rates in reservoir host species (rodents, shrews, and bats) and virus transmission to humans, is needed to prevent future outbreaks.

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Section: Resultsmentioning

confidence: 99%

Section: Studies On Forestry Workersmentioning

confidence: 99%

Occupational Hantavirus Infections in Agricultural and Forestry Workers: A Systematic Review and Metanalysis

Riccò

Peruzzi

Ranzieri

et al. 2021

Viruses

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“…Even though there is substantial evidence that certain occupational groups (e.g., farmers, forestry workers, etc.) are at greater risk of infection and, also, exhibit higher antibody prevalence than control groups [ 1 , 5 , 9 , 38 , 39 ], only 64.1% and 65.5% of participants acknowledged a higher risk for hantavirus infections among agricultural and forestry workers, respectively.…”

Section: Discussionmentioning

confidence: 99%

“…Second, while we specifically assessed the KAP of medical professionals, the available reports previously focused on residential and occupational groups, of variable health literacy. Eventually, it should be stressed that we specifically stressed the KAP of OP, whose potential importance in the management of hantavirus infections has been recently and strongly addressed [ 9 , 47 , 48 ], even though their actual understanding of these pathogens and related clinical syndromes largely remains undefined in both high- and middle-income countries.…”

Section: Discussionmentioning

confidence: 99%

“…As the main risk factor for hantavirus infections is represented by human-host (i.e., rodent) contact, such pathogens may represent an occupational risk agent for a broad array of professionals: veterinarians, laboratory scientists and technicians, military personnel, forestry workers and farmers [ 1 ]. Not coincidentally, studies performed on high-risk occupational groups from Western and North-European countries such as Spain [ 9 ], Germany [ 10 , 11 ], Netherlands [ 12 ], Hungary [ 13 ], Slovakia [ 14 ], Sweden [ 15 , 16 ] and Norway [ 17 ] have reported seroprevalence rates ranging from 3.0 to 9.1%, peaking to 30.6% in some selected subgroups, significantly exceeding those of the general population of the parent country.…”

Section: Introductionmentioning

confidence: 99%

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Hantaviruses in Agricultural and Forestry Workers: Knowledge, Attitudes and Practices in Italian Physicians

et al. 2021

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Hantaviruses are viral pathogens usually endemic in rodent populations. Human exposure follows inhalation of dusts contaminated with rodent excreta, and most individuals have been infected in occupational settings heavily contaminated with rodent droppings, such as agricultural and forestry. To date, knowledge, attitudes and practices of medical professionals, especially occupational physicians (OP), regarding hantavirus disease in at-risk workers have been scarcely investigated. We investigated these topics through a structured questionnaire administered through an online survey of 223 medical professionals (42.2% of them working as OP). Adequate general knowledge of hantavirus disease was found in 48.9% of respondents, with OP exhibiting a better understanding of clinical features of human hantavirus infections. OP aware of the endemic status of hantavirus in North-Eastern Italy exhibited higher risk perception for agricultural workers (odds ratio 21,193, 95% confidence interval 3.666–122.505). On the contrary, a better knowledge of hantaviruses was association with acknowledging an increased risk of hantavirus infection in forestry workers (odds ratio 5.880, 95% confidence interval 1.620–21.343). Hantavirus in Italy represent an often-overlooked biological risk in occupational settings. The lack of preventive immunization, the inappropriate risk perception and the unsatisfying awareness of hantavirus issues collectively stress the importance of appropriate information campaigns among health care providers.

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Congenital lymphocytic choriomeningitis virus: A review

et al. 2022

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Introduction Lymphocytic choriomeningitis virus (LCMV) uses rodents such as mice and hamsters as its principal reservoir. When women acquire LCMV during pregnancy because of contact with rodents, it can lead to congenital LCMV infection, which is associated with high mortality and morbidity. Although the number of cases reported in the literature is increasing, LCMV is rarely mentioned because a history of exposure to rodents is uncommon and mostly unknown. Objectives The main objective of this article was to summarize all morphological, antenatal, and postnatal abnormalities that may suggest a congenital LCMV infection. Methods We reviewed PubMed case reports and case series where an antenatal and/or a postnatal description of at least one case of congenital LCMV infection was documented. Results We found 70 cases of congenital LCMV infection, 68 of which had antenatal or postnatal brain abnormalities, which were mainly chorioretinitis (59/70), hydrocephaly (37/70), microcephaly (22/70), ventriculomegaly (11/70) and periventricular calcifications (11/70). Antenatal and postnatal extracerebral abnormalities were mainly small for gestational age, ascites, cardiomegaly or anemia. Other organ damage was rare, but could include skin abnormalities, hydrops or hepatosplenomegaly. Seventy percent (49/70) of cases had major cerebral abnormalities that could have been detected by antenatal ultrasound examination. Congenital LCMV infection is associated with a significant mortality rate (30%) and survivors often have severe neurologic sequelae. Conclusion LCMV is a rare congenital infection, but awareness of the various prenatal ultrasound morphological abnormalities should be improved, and LCMV should be considered when first‐line etiological explorations are negative, especially when the mother's medical history indicates exposure to rodents.

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Screening of Forestry Workers in Guadalajara Province (Spain) for Antibodies to Lymphocytic Choriomeningitis Virus, Hantavirus, Rickettsia spp. and Borrelia burgdorferi

Cited by 9 publications

References 37 publications

Occupational Hantavirus Infections in Agricultural and Forestry Workers: A Systematic Review and Metanalysis

Occupational Hantavirus Infections in Agricultural and Forestry Workers: A Systematic Review and Metanalysis

Hantaviruses in Agricultural and Forestry Workers: Knowledge, Attitudes and Practices in Italian Physicians

Congenital lymphocytic choriomeningitis virus: A review

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