Screening of crude extracts of six medicinal plants used in South-West Nigerian unorthodox medicine for anti-methicillin resistant Staphylococcus aureus activity

Akinyemi, Kabiru Olusegun; Oladapo, Olukayode; Okwara, Chidi E; Ibe, Christopher C; Fasure, Kehinde A

doi:10.1186/1472-6882-5-6

Cited by 309 publications

(236 citation statements)

References 16 publications

(14 reference statements)

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“…These results are consistent with previous reports on related plants regarding antibacterial activity (12). Earlier, it was noted that differences in the antibacterial activity are associated with secondary metabolites (tannin and phenol) (12,20).…”

Section: Discussionsupporting

confidence: 93%

Antimicrobial and cytotoxic activity of Alnus glutinosa (L.) Gaertn., A. incana (L.) Moench, and A. viridis (Chaix) DC. extracts

Dahija

Haverić²,

Čakar³

et al. 2016

JHSCI

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Introduction: The objective of the present study was to evaluate the antimicrobial and cytotoxic activities of water extracts of leaves and barks from Alnus glutinosa (L.) Gaertn., A. incana (L.) Moench, and A. viridis (Chaix) DC.Methods: The antimicrobial activities of extracts were tested against gram-negative and gram-positive bacteria as well as yeast strains by the agar diffusion method. The cell viability was determined by the Trypan blue dye exclusion method.Results: The largest diameters of inhibition zone (DIZ) were recorded with Staphylococcus aureus ATCC 6538 and Bacillus subtilis 168M. The highest percentage of cell viability was observed with water bark extracts of A. glutinosa (97.46%).Conclusions: Potential antimicrobial properties of A. glutinosa, A. incana, and A. viridis demonstrated in this study, as well as their low levels of toxicity, make them an interesting subject for further studies.

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Section: Discussionsupporting

confidence: 93%

Antimicrobial and cytotoxic activity of Alnus glutinosa (L.) Gaertn., A. incana (L.) Moench, and A. viridis (Chaix) DC. extracts

Dahija

Haverić²,

Čakar³

et al. 2016

JHSCI

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show abstract

“…The MIC of the extracts was determined according to methods described by Shahidi and Akinyemi et al [23,24] . Extracts were diluted to concentrations ranging from 6.25% to 25% for garlic, honey and a mixture of garlic with honey (1:1, v/v).…”

Section: Determination Of Micmentioning

confidence: 99%

“…Negative control tubes with no bacterial inoculation were simultaneously maintained. Tubes were incubated aerobically at 37 °C for 24 h. The MIC was defined as the lowest concentration of garlic extract that completely inhibits the growth of the organism.…”

Section: Determination Of Micmentioning

confidence: 99%

Combined antibacterial activity of stingless bee (Apis mellipodae) honey and garlic (Allium sativum) extracts against standard and clinical pathogenic bacteria

Andualem

2013

Asian Pacific Journal of Tropical Biomedicine

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“…The widespread use of antibiotics has resulted in increased bacterial resistance to existing drugs, a phenomenon which threatens public health (Kavase et al, 2001). The emergence and dissemination of antimicrobial resistance in bacteria has been well documented as a serious problem world wide (Cohen, 2000;Orrett, 2002 andAkinyemi et al, 2005).…”

Section: Introductionmentioning

confidence: 99%

Comparative study of the effect of bitter leaf extract and antibiotics (gentamycin and amoxicillin) on bacterial species isolated from wound

A.O¹

2017

EJBPR

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Skin is the major organ of the human body which plays a vital role in maintaining health of human being. Certain diseases defined as infectious or communicable diseases are caused by pathogenic organisms. Some of the most common causative microorganisms related with infections include Staphylococcus aureus, Mycobacterium species, Lactobacillus species, Entrococcus species, Enterobacter aerogenes and Corynebacterium species. Most of the diseases spread by the bacteria which invade inside the body through skin. Bacterial infections on skin are the common ailment for generation of other disease in the body. Bacterial diseases are type of infectious diseases caused by pathogenic bacteria. These infections disturb the body immune system and causes inflammation, tissue damage and thus resulting in delayed wound healing process. The present study was undertaken to investigate the antibacterial effect of bitter leaf extract on pathogenic organisms isolated from wound. The antibacterial activities of bitter leaf extract (V, amygdalina) were determined against wound pathogens isolated from our study using Disc diffusion method for antibiotic sensitivity. The prevalence of the isolated wound pathogens were Corynebacterium species (80%), Staphylococcus aureus (50%), and Enterobacter aerogenes (30%). All the extracts showed marked antibacterial activity but to varied zones of inhibition.

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Screening of crude extracts of six medicinal plants used in South-West Nigerian unorthodox medicine for anti-methicillin resistant Staphylococcus aureus activity

Cited by 309 publications

References 16 publications

Antimicrobial and cytotoxic activity of Alnus glutinosa (L.) Gaertn., A. incana (L.) Moench, and A. viridis (Chaix) DC. extracts

Antimicrobial and cytotoxic activity of Alnus glutinosa (L.) Gaertn., A. incana (L.) Moench, and A. viridis (Chaix) DC. extracts

Combined antibacterial activity of stingless bee (Apis mellipodae) honey and garlic (Allium sativum) extracts against standard and clinical pathogenic bacteria

Comparative study of the effect of bitter leaf extract and antibiotics (gentamycin and amoxicillin) on bacterial species isolated from wound

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