Screening of Chemical Composition, Antioxidant and Anticholinesterase Activity of Section Brevifilamentum of Origanum (L.) Species

Yilmaz, Hasibe; Çarıkçı, Sema; Kılıç, Turgut; Dırmencı, Tuncay; Arabacı, Turan; Gören, Ahmet

doi:10.25135/acg.rnp.56.17.04.029

Cited by 9 publications

(6 citation statements)

References 22 publications

(19 reference statements)

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“…So, there is an increasing demand in safer and natural antioxidants for food, biological and pharmaceutical systems. Also, there are increasing trends in consumer preference towards natural and safer antioxidants from plants origin [7].…”

Section: Previous Studiesmentioning

confidence: 99%

Antioxidant Activity of Flaxseed (Linum usitatissimum L.) shell and Analysis of Its Polyphenol Contents by LC-MS/MS

Han¹,

Yilmaz²,

Gülçin³

2018

Rec.Nat.Prod.

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Flaxseed (Linum usitatissimum L.) is important source of oil and protein for industrial, pharmaceutical, and nutritional applications. In order to estimate the effects of lyophilized aqueous extract of flaxseed shell (AEF) and evaporated ethanolic extract of flaxseed shell (EEF), we studied their DPPH, ABTS, DMPD and O 2•-scavenging effects. 3+ reducing ability, and Fe 2+ chelating activity. Also, α-tocopherol, BHA, trolox, and BHT were used as positive controls. The results clearly AEF and EEF demonstrated effective antioxidant activity. The quantity of p-hydroxybenzoic, vanillin, p-coumaric acid, ascorbic acid, ferulic acid, and ellagic acid were investigated by LC-MS/MS. The present study will introduce a novelty for further studies on the antioxidant effects of AEF and EEF.

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Section: Previous Studiesmentioning

confidence: 99%

Antioxidant Activity of Flaxseed (Linum usitatissimum L.) shell and Analysis of Its Polyphenol Contents by LC-MS/MS

Han¹,

Yilmaz²,

Gülçin³

2018

Rec.Nat.Prod.

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“…The antioxidant activities were measured based on 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging activity (24)(25)(26)(27)(28)(29)(30), β-carotene linoleic acid assays (24,26,30) and cupric (Cu 2+ ) ion reducing power assay (CUPRAC) (24,26,(30)(31)(32).…”

Section: Biological Activitymentioning

confidence: 99%

Investigation of Phenolic Compounds and Antioxidant Activity of Mentha spicata L. subsp. spicata and M. longifolia (L.) L. subsp. typhoides (Briq.) Harley Decoction and Infusion

Özer¹

2018

Journal of the Turkish Chemical Society Section A: Chemistry

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In the present study, phenolic compounds and antioxidant activity of decoction and infusion of aerial parts of Mentha spicata subsp. spicata and M. longifolia subsp. typhoides (Briq.) Harley were investigated. Phenolic contents of the decoction and infusion were analyzed using LC-MS/MS. Also, the antioxidant activity of the species was determined by three methods: 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging, β-carotene linoleic acid assays, and CUPRAC assays. Flavonoids and derivatives were the most abundant components of the M. spicata subsp. spicata decoction and M. longifolia subsp. typhoides decoction and infusion, whereas coumaric acids and derivatives were found to be the most abundant components of M. spicata subsp. spicata infusion. Particularly, the main compounds were determined as follow for M. spicata subsp. spicata decoction and infusion; caffeic acid and fumaric acid. Rosmarinic acid was detected in high amounts in M. longifolia subsp. typhoides decoction and infusion. For all the activity assays, infusion and decoction of the samples showed good activity. Cite this: Ozer Z. Investigation of Phenolic Compounds and Antioxidant Activity of Mentha spicata subsp. spicata and M. longifolia subsp. typhoides (Briq.) Harley Decoction and Infusion.

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“…Acetylcholinesterase (AChE) inhibition was examined using the method described by Ingkaninan [26,27]. Galantamine was used as the positive control.…”

Section: Acetylcholinesterase (Ache) Inhibition Assaymentioning

confidence: 99%

Bioassay Guided Isolation of Active Compounds from Alchemilla barbatiflora Juz.

Renda¹,

Özel²,

Barut³

et al. 2017

Rec. Nat. Prod.

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Abstract:The aerial parts of Alchemilla L. species (Rosaceae) are used internally as diuretic, laxative, tonic and externally for wound healing in Turkish folk medicine. Antioxidant effects of the extracts, fractions and isolated compounds from the aerial parts of A. barbatiflora Juz. were investigated with following methods: 1,1-diphenyl-2-picryl-hydrazyl (DPPH), and superoxide radical scavenging (SOD), phosphomolibdenum-reducing antioxidant power (PRAP), ferric-reducing antioxidant power (FRAP) assays. In addition, tyrosinase, α-glucosidase and acetylcholinesterase inhibition activities of samples were analyzed. The methanol extract from the aerial parts of plant was consecutively fractionated into four subextracts; n-hexane, chloroform, and remaining water extracts. Further studies were carried out on the most active water subextract and the fractions obtained from water subextract with column chromatography. Phytochemical studies on active fractions of the water subextract led to the isolation of seven metabolites including catechin (1) and a catechin dimer; procyanidin B3 (2), a flavonol glucuronide; quercetin-3-O-β-D-glucuronic acid (miquelianin) (3) with flavonoid glycosides; quercetin-3-O-β-D-galactoside (hyperoside) (4), quercetin-3-O-β-D-arabinoside (guaiaverin) (5), kaempferol-3-O-β-Dxylopyranoside (6) and kaempferol-3-O-(6″-coumaroyl-β-D-glycoside) (tiliroside) (7). Their structures were elucidated by spectral techniques (1D and 2D NMR). The experimental data verified that procyanidin B3 displayed remarkable enzyme inhibitory activity among the whole isolated compounds.

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Screening of Chemical Composition, Antioxidant and Anticholinesterase Activity of Section Brevifilamentum of Origanum (L.) Species

Cited by 9 publications

References 22 publications

Antioxidant Activity of Flaxseed (Linum usitatissimum L.) shell and Analysis of Its Polyphenol Contents by LC-MS/MS

Antioxidant Activity of Flaxseed (Linum usitatissimum L.) shell and Analysis of Its Polyphenol Contents by LC-MS/MS

Investigation of Phenolic Compounds and Antioxidant Activity of Mentha spicata L. subsp. spicata and M. longifolia (L.) L. subsp. typhoides (Briq.) Harley Decoction and Infusion

Bioassay Guided Isolation of Active Compounds from Alchemilla barbatiflora Juz.

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