Screening of biological activities of Polygonum maritimum L. from Algerian coast

Haci, Imad Abdelhamid El; Bekkara, Fawzia Atik; Mazari, Wissame; Hassani, Fayçal; Didi, Mohamed Amine

doi:10.1016/s2221-1691(13)60124-0

Cited by 22 publications

(21 citation statements)

References 27 publications

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“…azel showed that this plant has a significant antioxidant activity. These results corroborate those obtained in a recent study on Pancratium maritimun L. (Polygonaceae) developed by El‐Haci et al . and demonstrated that this plant has an important antioxidant activity.…”

Section: Resultssupporting

confidence: 92%

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Barks Essential Oil, Secondary Metabolites and Biological Activities of Four Organs of Tunisian Calligonum azel Maire

Bannour

Aouadhi

Khalfaoui

et al. 2016

Chemistry & Biodiversity

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This study is the first to investigate the chemical composition of barks essential oil (EO), secondary metabolites and biological activities of the MeOH and infusions extracts of seeds, leaves, barks and roots of Calligonum azel Maire (Polygonaceae) harvested from Tunisian desert. The gas chromatography/mass spectrometry (GC/MS) results showed the presence of fifty-four compounds in barks EO. The major components were: viridiflorol (14.6%), α-eudesmol (8.65%), trans-caryophyllene (6.72%), elemol (6.63%), β-eudesmol (6.21%). The obtained results showed that C. azel is a very rich plant in secondary metabolites. High contents in polyphenols, flavonoids and tannins were observed in both extracts of all studied organs. Significant differences were found between both extracts of the four organs. Thus, polyphenols and tannins were more abundant in leaves infusion extract, while, flavonoids showed a high level in barks extract. The antioxidant activity data demonstrated that all extracts showed strong antioxidant and radical scavenging activities. The MeOH extracts presented potential for antibacterial and antifungal activities against all tested microorganisms. The inhibition zones diameters and minimal inhibitrice concentration values were in the range of 9 - 15 mm and 2.5 - 20 μg/ml, respectively. This study demonstrated that C. azel can be regarded as an excellent plant source for natural antimicrobial agents.

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Section: Resultssupporting

confidence: 92%

“…In addition, our results corroborate those obtained in a study on C . comosum . This study showed that these plants are rich mainly in anthraquinones and flavonoids.…”

Section: Resultsmentioning

confidence: 73%

Barks Essential Oil, Secondary Metabolites and Biological Activities of Four Organs of Tunisian Calligonum azel Maire

Bannour

Aouadhi

Khalfaoui

et al. 2016

Chemistry & Biodiversity

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“…The genus Polygonum belongs to the family Polygonaceae, one of the dominant families in the flora of most countries, especially in the Northern Hemisphere [1]. Being native to Europe, Asia and Africa, Polygonum herbs have been used as traditional medicines in many different cultures for treating dysentery, articular pain, inflammation and diabetes [2][3][4].…”

Section: Introductionmentioning

confidence: 99%

“…Being native to Europe, Asia and Africa, Polygonum herbs have been used as traditional medicines in many different cultures for treating dysentery, articular pain, inflammation and diabetes [2][3][4]. As reported in recent publications, plants belonging to Polygonum genus are known to produce a large number of biologically important secondary metabolites, such as flavonoids, anthraquinones, stilbenoids, glycolipids and terpenes [1,[5][6][7]. These secondary metabolites are largely viewed as potential sources of novel anticancer and antiallergic agents, antiinflammatory drugs, antibiotics, insecticides and herbicides.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of anticancer and antimicrobial activities of the Polygonum maritimum ethanol extract

Jovanović

Srdiċ-Rajiċ

Svirčev

et al. 2018

ARCH BIOL SCI BELGRA

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Polygonum maritimum is a traditional herbal remedy that produces abundant flavonoid secondary metabolites. The ethanol extract of P. maritimum aerial parts (POM) was chemically characterized and tested for antimicrobial properties and cytotoxicity. Results of LC-MS/MS analysis showed high contents of gallic acid, epigallocatechin gallate and catechin, and significant amounts of quercetin-3-O-galactoside and quercetin-3-O-glucoside. Evaluation of the antifungal properties revealed that POM induced notable growth inhibition of Alternaria alternata (34.3%), Penicillium spp. (30.6%), Fusarium semitectum (20.2%) and Aspergillus spp. (19.6%). Evaluation of cytotoxicity against human hepatoma HepG2 cells included monitoring the effects of both POM alone and its combination with cytostatic doxorubicin (Dox). Cell viability, apoptosis and cell cycle distribution and the expression of antioxidant enzymes (superoxide-dismutases SOD1 and SOD2 and catalase) were determined. A dose-dependent decrease in cell viability was detected, but a remarkably stronger effect was obtained when POM and Dox were applied in combination as compared to individual treatments. IC 50 values were determined to be 393 μg/mL (POM) and 2.24 μg/mL (Dox) in combination, but 1153 μg/mL (POM) and 12.56 μg/mL (Dox) in a single treatment. The value of the Loewe index, determined for IC 50 , was notably lower than 1 (LI=0.51), clearly indicating synergism of POM and Dox. Additionally, POM and POM +Dox induced early/late apoptosis and G2/M cell cycle arrest. Furthermore, POM increased, while Dox decreased the expression levels of SODs and catalase. The obtained results encourage further examination of the potential use of POM in modern phytotherapy.

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“…Guizhou Miao medicine P. capitatum has antibacterial activity and can be used in bladder infection (Hu et al, 2014). Methanolic crude extract of aerial parts of P. maritimum showed a high antibacterial activity against gram-positive bacterial strains: Bacillus cereus, Bacillus subtilis, and Staphylococcus aureus with a highest MIC of 120 mg/ml (El-Haci et al, 2013). P. orientale extracts had protective effect against Clavibacter michiganense subsp.…”

Section: Antimicrobial Antiparasitic and Insecticidal Activitiesmentioning

confidence: 95%

Phytochemical and biological research of Polygoneae medicinal resources

Hao¹,

Gu²,

Xiao³

2015

Medicinal Plants

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Screening of biological activities of Polygonum maritimum L. from Algerian coast

Cited by 22 publications

References 27 publications

Barks Essential Oil, Secondary Metabolites and Biological Activities of Four Organs of Tunisian Calligonum azel Maire

Barks Essential Oil, Secondary Metabolites and Biological Activities of Four Organs of Tunisian Calligonum azel Maire

Evaluation of anticancer and antimicrobial activities of the Polygonum maritimum ethanol extract

Phytochemical and biological research of Polygoneae medicinal resources

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