Screening of Antioxidant Property and Phytochemical Constituents of Ethereal Extract of Vitex nigundo Linn Leaves

Fatema, Samreen; Farooqui, Mazahar; Gawade, Bhimraj; Arif, Pathan Mohd

doi:10.20902/ijctr.2018.110821

Cited by 4 publications

(2 citation statements)

References 10 publications

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“…The antioxidant activity was studied by using stable free radical DPPH (2, 2-diphenyl-1picrylhydrazyl) with the help of UVspectrophotometer in vitro assay [13][14][15][16]. 0.1 mM DPPH solution was prepared in ethanol solvent.…”

Section: Antioxidant Activitymentioning

confidence: 99%

Antioxidant Potential and GC-MS Analysis of Abrus precatorius Linn Leaves Ethanol Extract

Gawade¹,

Farooqui²

2021

CSIJ

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Aims: The aim of present study to evaluate the antioxidant potential of Abrus precatorius Linn leaves ethanol extract containing bioactive compounds on free radical scavenger using DPPH. Ethanol extract of Abrus precatorius Linn leaves was subjected to preliminary phytochemical screening and fraction of extract was detected by Gas Chromatography-Mass Spectrometry analysis. Methodology and Results: GC-MS analysis of ethanol leaves extract was carried out on Shimadzu GC-MS model number QP 2010S and revealed the presence of 18 phytochemical compounds, with mome inositol as a dominant component. Antioxidant potential of leaves ethanol extract was evaluated using DPPH free radical scavenging assay at five different doses as 5, 10, 20, 30, 40 and 50 μg/mL and showed significant DPPH free radical scavenging potential with the IC50 value of 33.37 μg/mL. The bioautography of extract showed that fractions with the most prominent antioxidant potential tended to contain secondary metabolites reported in preliminary phytochemical screening such as alkaloids, carbohydrates, protein and amino acids, glycoside, tannins, flavonoids, triterpenoids and phenolic compounds. The results evaluate and justify the traditional relevance of Abrus precatorius Linn leaves ethanol extract for free radical scavenging potential as a antioxidant and can be used as a lead for the isolation of the antioxidant bioactive chemical constituents in further study. Conclusion: Preliminary phytochemical screening reported various bioactive compounds in the ethanol extract of Abrus precatorius Linn leaves and identified by GC-MS. The extract exhibited greater free radical scavenging activity i.e. antioxidant potential. The presence of various bioactive phytocompounds justifies the therapeutic use of the Abrus precatorius Linn plant leaves for various ailments by traditional practitioners.

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Section: Antioxidant Activitymentioning

confidence: 99%

Antioxidant Potential and GC-MS Analysis of Abrus precatorius Linn Leaves Ethanol Extract

Gawade¹,

Farooqui²

2021

CSIJ

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“…Plants having great potential to produce compounds with different drug activity, through which humans can take benefit for the healthy life. Several infectious diseases can be treated with the traditional remedies [1]. From ancient time, humans are habitual to utilize plants and plant-derived products to cure and relief from physical and mental illness [2].…”

Section: Introductionmentioning

confidence: 99%

Phytochemical and Physicochemical Analysis of Microwave-Assisted Extraction Coriandrum Sativum L. Leaves and Its Biological Evaluation

Fatema

Farooqui²,

Arif

et al. 2019

Asian J Pharm Clin Res

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Objective: The main objective of the present work is to carry out the phytochemical constituent present and physicochemical analysis of microwave-assisted extract (MAE) of Coriandrum sativum leaves and to investigate its antibacterial activity. Methods: The powdered samples of the leaves were extracted and analyzed for physicochemical properties. Extraction was carried out for C. sativum using different solvents and used for phytochemical investigation. Infrared (IR) spectrum and antibacterial activity of MAE were carried out. Results: The results show that the percentage extract is different in the different solvents and also differs in phytochemical constituents. Phytochemicals present in the MAE also confirmed by IR spectroscopy. MAE is active against bacteria. Conclusion: The phytochemicals present in C. sativum is confirmed by IR spectrum and these phytochemicals responsible for antibacterial activity.

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Evaluation of the anti-inflammatory and antioxidant properties and isolation and characterization of a new bioactive compound, 3,4,9-trimethyl-7-propyldecanoic acid from Vitex negundo

Sivapalan,

Dharmalingam,

Ashokkumar

et al. 2024

Journal of Ethnopharmacology

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Screening of Antioxidant Property and Phytochemical Constituents of Ethereal Extract of Vitex nigundo Linn Leaves

Cited by 4 publications

References 10 publications

Antioxidant Potential and GC-MS Analysis of Abrus precatorius Linn Leaves Ethanol Extract

Antioxidant Potential and GC-MS Analysis of Abrus precatorius Linn Leaves Ethanol Extract

Phytochemical and Physicochemical Analysis of Microwave-Assisted Extraction Coriandrum Sativum L. Leaves and Its Biological Evaluation

Evaluation of the anti-inflammatory and antioxidant properties and isolation and characterization of a new bioactive compound, 3,4,9-trimethyl-7-propyldecanoic acid from Vitex negundo

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