“…However, the rapid development and wide application of high-resolution-timeof-flight-mass spectrometry (HR-ToF-MS) in the last decade allows us to look at the qualitative problem from a different point of view. [9][10][11][12][13][14][15][16] This analyzer owns high fullspectral sensitivity with high mass resolution required for wide-scope screening. The accurate mass spectra can be used for both target and/or non-target processing, which depends on the aim of the analysis.…”
Section: European Journal Of Mass Spectrometrymentioning
A post-target analysis method based on gas chromatography coupled to a high-resolution quadrupole time-of-flight mass analyzer is applied for the investigation of volatile compounds in Fructus Amomi. A series of narrow window extracted ion chromatograms at selected characteristic ions were performed. Chromatographic peaks with the same retention time in different extracted ion chromatograms was used to screen out the candidate compound. Identification was achieved by the accurate masses of several characteristic ions and the retention index of the peak. Forty six compounds, including 12 monoterpene compounds, were identified by conventional static headspace gas chromatography mass spectrometry and another six monoterpene compounds were found and identified by the post-target method. Post-target analysis is a useful strategy in qualitative research of natural products.
“…However, the rapid development and wide application of high-resolution-timeof-flight-mass spectrometry (HR-ToF-MS) in the last decade allows us to look at the qualitative problem from a different point of view. [9][10][11][12][13][14][15][16] This analyzer owns high fullspectral sensitivity with high mass resolution required for wide-scope screening. The accurate mass spectra can be used for both target and/or non-target processing, which depends on the aim of the analysis.…”
Section: European Journal Of Mass Spectrometrymentioning
A post-target analysis method based on gas chromatography coupled to a high-resolution quadrupole time-of-flight mass analyzer is applied for the investigation of volatile compounds in Fructus Amomi. A series of narrow window extracted ion chromatograms at selected characteristic ions were performed. Chromatographic peaks with the same retention time in different extracted ion chromatograms was used to screen out the candidate compound. Identification was achieved by the accurate masses of several characteristic ions and the retention index of the peak. Forty six compounds, including 12 monoterpene compounds, were identified by conventional static headspace gas chromatography mass spectrometry and another six monoterpene compounds were found and identified by the post-target method. Post-target analysis is a useful strategy in qualitative research of natural products.
“…The strong potential of Orbitrap for identification purposes comes from its high resolution, as recently illustrated for different organic pollutants [6,8,24]. However, Orbitrap has been much less used for quantification purposes.…”
Section: Application To Sewage Water Samplesmentioning
“…Els mètodes qualitatius d'ampli screening -basats en cromatografia/ HRMS (Kaufmann, 2012;-units a mètodes quantitatius molt sensibles -basats en acoblaments cromatografia/MS en tàndem-aporten el coneixement necessari en àmbits tan diversos com ara medi ambient, seguretat alimentària, toxicologia, control antidopatge o anàlisi forense (Díaz, 2012;Peters, 2010;Hernández 2011b;Picó, 2008).…”
Section: Investigació De Compostos Diana (Target Analysis) I De Compounclassified
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