“…[3][4][5] In pediatric age, pulmonary AVMs (PAVMs) occur in 30% to 45% of HHT patients, 25% to 40% of those will develop PAVMrelated symptoms. [4][5][6] Manifestations of PAVMs include hypoxemia features (dyspnea, cyanosis, and polycythemia), hemoptysis, as well as risk of developing neurological complications, such as stroke or cerebral abscess, by paradoxical embolization. 7,8 Neurological complications can be associated with respiratory symptoms or, in some cases, occur as the first clinical manifestation of otherwise asymptomatic PAVMs.…”