Screening for obstructive sleep apnoea in obesity and diabetes – potential for future approaches

Seetho, Ian; Wilding, John

doi:10.1111/eci.12083

Cited by 21 publications

(18 citation statements)

References 134 publications

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“…3,4 Many studies have demonstrated that OSAS should be diagnosed and treated at an early stage, 5,6 because OSAS can cause serious traffic accidents, 7 long-term hypoxic stress, 8 a pro-inflammatory state, 9 and endothelial dysfunction 10 in various organs. Although some patients with undiagnosed OSAS may visit an otolaryngology department to be treated for their snoring, other patients may visit a psychiatry department for a sense of malaise or a urology department for nocturia or erectile dysfunction.…”

Section: Introductionmentioning

confidence: 99%

Obstructive sleep apnea syndrome should be considered as a cause of nocturia in younger patients without other voiding symptoms

Maeda

Fukunaga

Nagata

et al. 2016

CUAJ

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Introduction: This study aimed to evaluate urination frequency among patients with obstructive sleep apnea syndrome (OSAS) and the effect of continuous positive airway pressure (CPAP) treatment.Methods: We evaluated 138 men with moderate-to-severe OSAS by using polysomnography. Urination status was assessed at baseline and three months using the International Prostate Symptom Score and Overactive Bladder Symptom Score. Nocturia was defined as ≥2 nighttime urinations and patients were classified into Group A (<50 years old with nocturia), Group B (≥50 years old with nocturia), and Group C (patients without nocturia). OSAS severity and other urinary symptoms were also evaluated.Results: Patients with nocturia exhibited more severe OSAS, compared to patients without nocturia (apnea-hypopnea index [AHI]: 52.0 vs. 44.7; p=0.021). Group A had the worst AHI, but did not have additional voiding symptoms, compared to Group B (p<0.001). The number of urinations was significantly correlated with OSAS severity in <50-year-old patients (p=0.013). CPAP reduced the number of urinations in Group A (75% of patients) and Group B (90% of patients). Patients with and without improved nocturia exhibited significant differences in their baseline OSAS severity (AHI: 53.7 vs. 37.3; p=0.042).Conclusions: OSAS severity was associated with the number of urinations in <50-year-old patients. CPAP decreased the nocturia frequency in 85% of patients with nocturia and was most effective in patients with severe AHI. However, additional studies should evaluate voiding volume in order to elucidate the mechanism of nocturia in patients with OSAS.

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Section: Introductionmentioning

confidence: 99%

Obstructive sleep apnea syndrome should be considered as a cause of nocturia in younger patients without other voiding symptoms

Maeda

Fukunaga

Nagata

et al. 2016

CUAJ

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“…28 Thus, our study adds to the growing body of literature that supports expansion of testing in these populations which may be at higher risk than previously estimated. 29,30 …”

Section: Discussionmentioning

confidence: 99%

Feasibility of Portable Sleep Monitors to Detect Obstructive Sleep Apnea (OSA) in a Vulnerable Urban Population

Nickerson

Lee

Nedelman

et al. 2015

The Journal of the American Board of Family Medicine

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Purpose Portable sleep monitors may offer a convenient method to expand detection of obstructive sleep apnea (OSA), yet few studies have evaluated this technology in vulnerable populations. We therefore aimed to assess the feasibility and acceptability of portable sleep monitors for detection of OSA in a prediabetic, urban minority population. Methods We recruited a convenience sample of participants at their 12-month follow-up for a community-partnered, peer-led lifestyle intervention aimed to prevent diabetes in prediabetic and overweight patients in this prospective mixed-methods pilot study. All participants wore portable sleep monitors overnight at home. We qualitatively explored perceptions about OSA and portable monitors in a subset of participants. Results We tested 72 people, predominantly non-White, female, Spanish speaking, uninsured, and of low income. Use of portable sleep monitors was feasible: 100% of the monitors were returned and all participants received results. We detected OSA in 49% (defined as an Apnea-Hypopnea Index [AHI] >5) and moderate-severe OSA in 14% (AHI >15) requiring treatment in 14%. In 21 qualitative interviews, participants supported increased use of portable sleep monitors in their community, were appropriately concerned that OSA could cause progression to diabetes, and thought weight loss could prevent or improve OSA. Conclusions Portable sleep monitors may represent a feasible method for detecting OSA in high-risk urban minority populations.

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“…44 Weight or BMI should not be the sole measurements considered as they do not account for the distribution of body fat or variance in cephalometric measurements such as the size of the tongue or soft palate. 45 Overnight sleep studies at a sleep center or home devices can be used to diagnose OSA. The advantage of a home screening device is the ease of use, short set-up time and low cost.…”

Section: Prevalence and Screeningmentioning

confidence: 99%

Obesity, obstructive sleep apnea and type 2 diabetes mellitus: Epidemiology and pathophysiologic insights

Jehan

Myers

Zizi

et al. 2018

SMDIJ

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Screening for obstructive sleep apnoea in obesity and diabetes – potential for future approaches

Cited by 21 publications

References 134 publications

Obstructive sleep apnea syndrome should be considered as a cause of nocturia in younger patients without other voiding symptoms

Obstructive sleep apnea syndrome should be considered as a cause of nocturia in younger patients without other voiding symptoms

Feasibility of Portable Sleep Monitors to Detect Obstructive Sleep Apnea (OSA) in a Vulnerable Urban Population

Obesity, obstructive sleep apnea and type 2 diabetes mellitus: Epidemiology and pathophysiologic insights

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