Screening for obstructive sleep apnea among individuals with severe mental illness at a primary care clinic

Alam, Abdulkader; Chengappa, K. N. Roy; Ghinassi, Frank

doi:10.1016/j.genhosppsych.2012.06.015

Cited by 38 publications

(19 citation statements)

References 44 publications

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“…While our findings relate to OSA risk, this is consistent with the literature indicating individuals with severe mental illness 27,48 and/or psychological distress, such as depression or anxiety, have a higher prevalence of OSA. As our study shows an association between moderate depression and anxiety and risk of OSA, current literature supports a bidirectional relationship.…”

Section: Discussionsupporting

confidence: 92%

“…As our study shows an association between moderate depression and anxiety and risk of OSA, current literature supports a bidirectional relationship. 8,24,25,28,29,48 Additionally, older age represented an independent predictor of OSA risk. This finding identified older Non-Hispanic Black adults with metabolic syndrome, who presented with anxiety or depression as a high risk group for OSA.…”

Section: Discussionmentioning

confidence: 95%

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Obstructive sleep apnea risk and psychological health among non-Hispanic blacks in the Metabolic Syndrome Outcome (MetSO) cohort study

et al. 2015

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Introduction This study assessed associations of depression and anxiety with risk of OSA among Non-Hispanic Blacks in the Metabolic Syndrome Outcome (MetSO) study. Method 1,035 patients provided data for the analysis. ARES™ score ≥ 6 defined high OSA risk. Moderate depression was defined by a CES-D score ≥ 16. Moderate anxiety was measured by a BAI score ≥ 16. Results The mean age was 62 ± 14 years; 70% were female. 93% were diagnosed with hypertension; 61%, diabetes; and 72%, dyslipidemia; 90% were overweight/obese; 33% had a history of heart disease and 10% had a stroke. Logistic regression analysis, adjusting for age and gender, showed that patients with depression had nearly a two-fold increased odds of being at risk for OSA (OR = 1.75, 95% CI = 1.02–2.98, p < .05). Patients with anxiety had a three-fold increased odds of being at risk for OSA (OR = 3.30, 95% CI = 2.11–5.15, p < .01). After adjusting for marital status and income, patients with anxiety had a 6% increase in OSA risk (OR=1.06, 95% CI= 1.04–1.09, p<.05) but depression was no longer significant. Conclusion Our results suggest that Non-Hispanic Blacks with metabolic syndrome who experience anxiety and/or depression should be screened for OSA.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionmentioning

confidence: 95%

Obstructive sleep apnea risk and psychological health among non-Hispanic blacks in the Metabolic Syndrome Outcome (MetSO) cohort study

et al. 2015

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“…23–25 The STOP-Bang Questionnaire has been widely used in the general population, including with medical, surgical, and psychiatric patients. 32 …”

Section: Methodsmentioning

confidence: 99%

Association of Obstructive Sleep Apnea with Episodic Memory and Cerebral Microvascular Pathology: A Preliminary Study

Kerner

Roose

Pelton

et al. 2017

The American Journal of Geriatric Psychiatry

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Objectives Evaluate the impact of obstructive sleep apnea (OSA) on neurocognitive function and brain morphology in older adults with depression and cognitive impairment. Methods We prospectively screened OSA with the STOP-Bang questionnaire in the last 25 patients enrolled into the Donepezil Treatment of Cognitive Impairment and Depression (DOTCODE) trial. High and low probability of OSA were defined as a STOP-Bang score of ≥5 (h-OSA) and of <5 (l-OSA). Baseline MRI was used to evaluate brain morphology. The initial 16 weeks of antidepressant treatment were part of the DOTCODE trial. Results After 16 weeks of antidepressant treatment, the h-OSA group performed significantly worse on the Selective Reminding Test (SRT) delayed recall task than the l-OSA group, controlling for baseline performance (F=19.1, df=1,22, p<0.001). In nineteen out of 25 participants who underwent brain MRI, the h-OSA group had significantly greater volumes of MRI hyperintensities in deep white matter, periventricular white matter, and subcortical gray matter compared to the l-OSA group. There was no significant association between OSA and hippocampal or entorhinal cortex volumes in our sample, even after controlling for intracranial volume. Conclusions OSA is associated with impaired verbal episodic memory and microvascular damage in older adults with depression and cognitive impairment. One possibility is that by contributing to cerebral microvascular damage, OSA may exacerbate progressive memory decline.

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“…Thus, this issue is largely outside the scope of this paper. But it should be noted that sleep apnoea often presents as daytime sleepiness or non-restorative sleep (Alam et al, 2012; Cruz et al, 2012; Lal et al, 2012; Lee et al, 2012; Sunwoo et al, 2012) and sometimes as insomnia (Al-Jawder & Bahammam, 2012; Glidewell et al, 2012). Sleep apnoea is associated with significant sleep fragmentation (Bianchi et al, 2012) which may be one of the causal pathways linking this disorder to poor sleep, though the risks are probably largely due to the intermittent hypoxia and co-morbid obesity (Pak et al, 2014).…”

Section: Cardiometabolic Disease Risk Associated With Sleep Disturbancementioning

confidence: 99%

Addressing sleep disturbances: An opportunity to prevent cardiometabolic disease?

Grandner

2014

International Review of Psychiatry

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There is increasing awareness of the role of sleep disturbance as an important factor in health and disease. Although subclinical sleep disturbances (insufficient sleep duration or inadequate sleep quality) may be difficult to assess with conceptual and/or methodological clarity, this review attempts to summarize and synthesize these findings. First, the concept of sleep disturbance in a public health context is introduced, to provide context and rationale. Second, operational definitions of ‘cardiometabolic disease’ and ‘sleep disturbance’ are offered, to address many unclear operationalizations. Third, the extant literature is summarized regarding short or long sleep duration and/or insufficient sleep, insomnia and insomnia symptoms, general (non-specific sleep disturbances), circadian rhythm abnormalities that result in sleep disturbances, and, briefly, sleep-disordered breathing. Fourth, the review highlights the social/behavioural context of sleep, including discussions of sleep and race/ethnicity, socio-economic position, and other social/environmental factors, in order to place these findings in a social-environmental context relevant to public health. Fifth, the review highlights the issue of sleep as a domain of health behaviour and addresses issues regarding development of healthy sleep interventions. Finally, a research agenda of future directions is proposed.

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Screening for obstructive sleep apnea among individuals with severe mental illness at a primary care clinic

Cited by 38 publications

References 44 publications

Obstructive sleep apnea risk and psychological health among non-Hispanic blacks in the Metabolic Syndrome Outcome (MetSO) cohort study

Obstructive sleep apnea risk and psychological health among non-Hispanic blacks in the Metabolic Syndrome Outcome (MetSO) cohort study

Association of Obstructive Sleep Apnea with Episodic Memory and Cerebral Microvascular Pathology: A Preliminary Study

Addressing sleep disturbances: An opportunity to prevent cardiometabolic disease?

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