1998
DOI: 10.1002/hep.510270140
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Screening for hepatocellular carcinoma

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Cited by 367 publications
(255 citation statements)
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References 67 publications
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“…US is the most widely used modality for HCC screening and surveillance, largely due to its relatively low costs and ready accessibility [190]. US as a screening test in HBsAg carriers showed a sensitivity of 71% and a specificity of 93%, but its positive predictive value is only 14% [191]. Some reports suggest the use of new techniques such as CT or MRI as promising alternative surveillance tools [192,193].…”
Section: Ct Mri and Other Imaging Modalitiesmentioning
confidence: 99%
“…US is the most widely used modality for HCC screening and surveillance, largely due to its relatively low costs and ready accessibility [190]. US as a screening test in HBsAg carriers showed a sensitivity of 71% and a specificity of 93%, but its positive predictive value is only 14% [191]. Some reports suggest the use of new techniques such as CT or MRI as promising alternative surveillance tools [192,193].…”
Section: Ct Mri and Other Imaging Modalitiesmentioning
confidence: 99%
“…In prospective cohort studies, nearly 1 in 5 patients were nonadherent with provider recommendations for HCC surveillance. (10,11) The cancer-screening literature has applied theoretical models of behavior change and demonstrated that patients' poor knowledge, negative attitudes, or perceived barriers to cancer screening may be associated with lower screening rates. (12,13) However, most studies evaluating HCC surveillance correlates have primarily focused on patient sociodemographic and clinical characteristics.…”
Section: Conclusion-patientsmentioning
confidence: 99%
“…In contrast, a`febrile' form of HCC, characterized by leucocytosis, fever, and necrosis within a poorly di erentiated tumor, is common in South African blacks (Okuda, 1997). While these observations suggest an underlying sequence of steps, a major problem in diagnosis and prognosis is the lack of molecular markers that characterize the pathogenic pathways that contribute to HCC (Collier and Sherman, 1998). This knowledge would help to identify patients with early HCC and to devise speciĀ®c intervention strategies based upon these biochemical changes.…”
Section: Introductionmentioning
confidence: 99%