Screening for Frailty and Sarcopenia Among Older Persons in Medical Outpatient Clinics and its Associations With Healthcare Burden

Tan, Li Feng; Lim, Zhen Yu; Choe, Rachel; Seetharaman, Santhosh Kumar; Merchant, Reshma Aziz

doi:10.1016/j.jamda.2017.01.004

Cited by 77 publications

(58 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Moreover, in the present study, the prevalence of SARC-F ≥4 increased with age, comorbidities, depressive symptoms, and frailty, in agreement with the findings of previous studies [12,13,15,30]. Several studies have demonstrated an overlap between frailty and sarcopenia [31,32]. The common theme in these two syndromes is physical function impairment [33], and sarcopenia is a major cause of frailty.…”

Section: Discussionsupporting

confidence: 92%

SARC‐F Questionnaire: Rapid and Easy Tool for Identifying Physical Limitations in Hemodialysis Patients

Yamamoto

Matsuzawa

Harada

et al. 2019

JCSM Clinical Reports

View full text Add to dashboard Cite

Background SARC-F is a simple questionnaire for rapidly assessing physical function and screening for sarcopenia. This study aimed to determine whether the SARC-F questionnaire is useful for identifying impaired physical function and the risk of physical limitations in hemodialysis patients. Methods and resultsThis cross-sectional study included 281 patients undergoing hemodialysis at two dialysis units. SARC-F, handgrip strength, leg strength, one-leg standing time, usual gait speed, and short physical performance battery (SPPB) score were measured. Patients were classified according to the SARC-F score (SARC-F <4 and SARC-F ≥4), indicating the risk of sarcopenia. Furthermore, we defined physical limitations as handgrip strength of <26 kg for men and <18 kg for women, leg strength of <40%, usual gait speed of ≤0.8 m/s, and SPPB score of ≤8 points. To calculate the areas under the curves (AUCs) of the SARC-F score for physical limitations, receiver-operating characteristic curve analysis was performed. SARC-F ≥4 was observed in 75 (26.7 %) hemodialysis patients. The SARC-F ≥4 group had a significantly lower handgrip and leg strength, shorter one-leg standing time, slower usual gait speed, and lower SPPB score than the SARC-F <4 group, even after adjusting for potential confounders (all P <0.001). Further, SARC-F demonstrated good accuracy in identifying the risk of physical limitations (all AUCs > 0.75). Conclusions The SARC-F questionnaire is useful for screening impaired physical function and for identifying the risk of physical limitations in hemodialysis patients and can be easily and rapidly administered to this patient group in clinical practice.

show abstract

Section: Discussionsupporting

confidence: 92%

SARC‐F Questionnaire: Rapid and Easy Tool for Identifying Physical Limitations in Hemodialysis Patients

Yamamoto

Matsuzawa

Harada

et al. 2019

JCSM Clinical Reports

View full text Add to dashboard Cite

show abstract

“…The majority of studies indicate that falls are more common in frail than in nonfrail elderly (33)(34)(35). A new study conducted by Tan et al demonstrated that frailty is associated with a higher number of falls and falls with serious consequences (36). Bandeen et al determined that the incidence of falls in the past year was 30.5% in the robust population, 32.9% in prefrail patients, and 54.9% in frail patients (25).…”

Section: Discussionmentioning

confidence: 99%

Quality of life and fall risk in frail hospitalized elderly patients

Öztürk¹,

Özdemir²,

Türkbeyler³

et al. 2017

Turk J Med Sci

View full text Add to dashboard Cite

Background/aim: Frailty is a complex, multifactorial, and important geriatric syndrome characterized by decline in physiological reserves and functional deficiency in multiple systems. The aim of the current study is to investigate the prevalence of frailty and to determine the correlation between quality of life (QoL) and falling risk in geriatric hospitalized patients.Materials and methods: A total of 420 patients, aged 65 years and above, were enrolled in the study. All participants were hospitalized at a university hospital in the internal medicine clinics. The Cardiovascular Health Study (CHS) frailty scale, Health-Related Quality of Life Short Form (SF-36) scale, and Hendrich II Fall Risk Model were administered to the patients. Demographic data of patients, number of chronic diseases, and information on used medication were also collected. Results:The median age of patients was 71.9 ± 6.3 years and 49.5% of the patients were female. By applying the CHS frailty scale, the proportion of frail patients was determined to be 65.5%. There were statistically significant differences among quality of life mean scores of robust, prefrail, and frail patients (P < 0.001). Frail patients had the lowest scores in all SF-36 subgroups. Eighty-three (19.8%) patients were in the low-risk group while 337 (80.2%) were high-risk according to the Hendrich II Fall Risk Model. The rate of patients with high falling risk and poor QoL reached a maximum in the frail group (96%). Conclusion:Frailty is an important geriatric syndrome in elderly hospitalized patients. Poor QoL and high falling risk are issues commonly experienced with frailty.

show abstract

“…Aging-related loss of muscle mass and function has been associated with increased risk of falls and fractures and loss of independence among older individuals (1,2). Furthermore, recent cohort studies have shown that reduced muscle mass alone is associated with an increased risk of diabetes, cardiovascular disease (3,4), and higher mortality (5) among older individuals, highlighting the importance of skeletal muscle to the modulation of metabolism.…”

mentioning

confidence: 99%

Relationship between Dietary Protein or Essential Amino Acid Intake and Training-Induced Muscle Hypertrophy among Older Individuals

Yoshii

Sato

Ogasawara

et al. 2017

Journal of Nutritional Science and Vitaminology, J Nutr Sci Vit

View full text Add to dashboard Cite

Summary Dietary protein intake is critical for maintaining an optimal muscle mass, especially among older individuals. Although protein supplementation during resistance training (RT) has been shown to further augment training-induced muscle mass in older individuals, the impact of daily variations in protein intake on training-induced muscle mass has not been explored thus far. Therefore, this study aimed to investigate the relationship between the dietary protein and amino acid intake and RT-induced muscle hypertrophy among older individuals. Ten healthy older men (n510; mean age56962 y; body weight (BW)561.562.2 kg; height51.6560.02 m) participated in progressive RT performed 3 times/wk for 12 wk. Body composition (using DXA) and nutritional assessments (using a 3-d dietary record) were performed before and after the training period. Leg lean mass (LLM) increased significantly (15.060.8 vs. 15.460.8 kg, p,0.05) after RT, with no change in dietary nutrient intake. The average dietary protein intake was 1.6260.11 g/kg BW/d, while essential amino acids was 600651 mg/kg BW/d. Although the correlation between the increase in LLM and dietary protein intake was not significant, a significant correlation was found between the increase in LLM and dietary essential amino acid (EAA) intake. Furthermore, there were significant correlations between the increase in LLM and protein as well as EAA (especially leucine) intake at breakfast among subjects with suboptimal protein intake (p,0.05). Our study findings indicate that dietary protein as well as EAA intake may be significant contributing factors in muscle hypertrophic response during RT among healthy older men.

show abstract

Screening for Frailty and Sarcopenia Among Older Persons in Medical Outpatient Clinics and its Associations With Healthcare Burden

Cited by 77 publications

References 26 publications

SARC‐F Questionnaire: Rapid and Easy Tool for Identifying Physical Limitations in Hemodialysis Patients

SARC‐F Questionnaire: Rapid and Easy Tool for Identifying Physical Limitations in Hemodialysis Patients

Quality of life and fall risk in frail hospitalized elderly patients

Relationship between Dietary Protein or Essential Amino Acid Intake and Training-Induced Muscle Hypertrophy among Older Individuals

Contact Info

Product

Resources

About