“…Several studies have also been carried out in different populations of subjects including ID, AUT, or those with special educational needs, to both assess the prevalence of FXS among these populations and to identify subjects with FXS, which is very important for families. In the above studies, using both cytogenetic and molecular approaches, the full mutation rate varies between 0.5 and 16 % and the premutation rate varies between 0 and 0.8 % (Biancalana et al 2004; Blomquist et al 1985; Brown et al 1986; de Vries et al 1998; de Vries et al 1997; Hecimovic et al 2002; Major et al 2003; Mazzocco et al 1997; Mila et al 1997; Pandey et al 2002; Patsalis et al 1999; Pouya et al 2009; Reddy 2005; Schaefer and Lutz 2006; Sharma et al 2001; Syrrou et al 1998; Watson et al 1984; Yuhas et al 2009). A multicenter study conducted in Sweden (Blomquist et al 1985) found FXS in 16 % of boys with infantile autism, and a multicenter survey among individuals with autism found 13 % were positive for FXS (Brown et al 1986).…”