Screening for diabetes among tuberculosis patients: a nationwide population-based study in Egypt

Abstract

BackgroundThe prevalence of type 2 diabetes mellitus (DM) is increasing rapidly in Egypt and considered one of the major health problems in the Eastern Mediterranean region.ObjectivesTo measure the prevalence of diabetes and detect the undiagnosed cases of diabetes mellitus among patient with tuberculosis.MethodsStudy Design: Nationwide population-based study. To diagnose DM among TB patients, we used a fasting blood sugar level of ≥ 126 mg/dl and a post-prandial blood glucose test result of ≥ 200 mg/dl.ResultsScreening for DM among 1435 TB patients' with no history of DM detected 30 new cases of DM, with a case detection rate of 2.09%. The highest screening yields were among TB patients aged ≥ 40 years, females and those with pulmonary TB. The number needed to screen (NNS) TB patients for detecting one new case of DM was 48 while the lowest values were for older age (NNS=27) and females (NNS=29).ConclusionOlder age and being females and those with pulmonary type of TB were more prone to the double burden of TB and DM. Identifying cases with double burden of diseases will improve the proper management of both diseases and prevent complications.

<p>Diabetes Mellitus and Tuberculosis Comorbidity and Associated Factors Among Bale Zone Health Institutions, Southeast Ethiopia</p>

“…This finding was comparable with study conducted in Egypt 28 and Amhara Region. 23 However, the present study was inconsistent with study conducted in Bhopal India and Italy.…”

“… 25 The finding of this study was higher compared to studies conducted in Sri Lanka (2%), 26 Mozambique (1%) 27 and Egypt (2.09%). 28 The possible reason might be due study area and also might be due methods used to screen for diabetes mellitus. Screening of diabetes mellitus using different methods can affect the prevalence.…”

Gradient association between pulmonary tuberculosis and diabetes mellitus among households with a tuberculosis case: a contact tracing-based study

“…The efficiency of a screening program can be assessed from ‘additional yield’ and ‘number needed to screen’. The additional yield is the percentage of the newly diagnosed cases by screening divided by a total number of known and new cases of interested disease 12 , 13 . The number needed to screen (NNS) is the number of people who need to be tested to find one positive case 14 .…”

Infusion of bone marrow mesenchymal stem cells alleviates insulin resistance and initiates pancreatic regeneration in experimental type 2 diabetic-rats

“…The development of type 2 diabetes mellitus (T2DM), accounting for 90 % of all diabetes cases, has been determined by both genetic and environmental factors [2] . The prevalence of T2DM is increasing rapidly in Egypt and considered one of the major health problems in the Eastern Mediterranean region [3] . T2DM is characterized by disturbances in the metabolism of lipids and carbohydrates, as well as insulin resistance and dysfunction in pancreatic β-cells [4] .…”