Screening for Depression and Suicide Risk in Adults

Barry, Michael J.; Nicholson, Wanda K; Silverstein, Michael; Chelmow, David; Coker, Tumaini R.; Davidson, Karina W.; Davis, Esa M.; Donahue, Katrina E; Jaén, Carlos Roberto; Li, Li; Ogedegbe, Gbenga; Pbert, Lori; Rao, Goutham; Ruiz, John; Stevermer, James J.; Tsevat, Joel; Underwood, Sandra Millon; Wong, John B.

doi:10.1001/jama.2023.9297

Cited by 54 publications

(9 citation statements)

References 55 publications

(210 reference statements)

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“…Although the mental health problems have not been specified, the results are consistent with those of the other studies ( 48 ). Depression and anxiety assessment scales “can be used to identify at-risk individuals who need further evaluation.” Many screening instruments are available in gynecological practice (i.e., the Beck Depression Inventory and the State–Trait Anxiety Inventory), taking into consideration that “the primary health care can overlook up to 50% of patients with depression” ( 49 , 50 ).…”

Section: Discussionmentioning

confidence: 99%

“…Recommendations for Well-Woman Care (A Well-Woman Chart) was developed by the Women’s Preventive Services Initiative (WPSI), US Preventive Services Task Force (USPSTF), and ACOG (Statement on Depression Screening), a framework for integrating preventive women’s health services into clinical practice: “depression and anxiety screening, using validated questionnaires is recommended annually” ( 49 , 50 ), also because “women with depression are more likely to suffer from sexual dysfunction than others” ( 51 ).…”

Section: Discussionmentioning

confidence: 99%

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Women’s sexual health improvement: sexual quality of life and pelvic floor muscle assessment in asymptomatic women

Baszak-Radomańska,

Wańczyk-Baszak,

Paszkowski

2024

Front. Med.

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IntroductionProblems related to the quality of sexual life in gynecological practice are usually neglected. This study aimed to highlight the significance of this area of concern and evaluate the usefulness of tools, such as patient-reported outcomes (PROs) and pelvic floor examination, to improve women’s sexual wellbeing and to identify predictors of poor quality of sexual life during the well-woman annual visit.MethodsA cross-sectional study was designed to examine 300 healthy women to determine whether the sexual quality of life (SQOL) questionnaire (on electronic devices) and pelvic floor muscle assessment (the vulva, anus, muscles, and periurethral (VAMP) protocol) of asymptomatic women during the annual bimanual examination (BME) help differentiate patients who would benefit from discussing sexual problems with a gynecologist. Dyspareunia was an exclusion criterion.ResultsThe majority of subjects experienced high sexual wellbeing (82.0% with SQOL score of ≥84), with a mean of 85.7 points. SQOL scores were lower for psychiatric disorders or symptoms (37.0% of subjects), although they did not correlate with age, BMI, parity, contraception use, history of vulvovaginal symptoms, neurosurgical/orthopedic problems, and rectal, bowel, or bladder symptoms. Patients with dyspareunia (16.0% of participants, although they denied it during the face-to-face consultation) had a 3.6 times higher prevalence of low or moderate quality of sexual life. The VAMP protocol score was low in asymptomatic women, 33.0% met positive criteria (VAMP+, NRS ≥3) for pelvic floor dysfunction (overactivity), although at borderline levels. VAMP+ was positively correlated with chronic pain and genitourinary symptoms, but neither with dyspareunia nor incontinence, and was unrelated to the SQOL score (p = 0.151).ConclusionWomen’s sexual health is a global health priority. Finding a way to start a discussion with an asymptomatic patient is crucial to increasing patients’ interest in disclosing a sexual health problem to be resolved. PROs or simple questions about sexual wellbeing direct the discussion mainly toward the at-risk group for sexual deterioration: those with mental health problems and women with dyspareunia. Dyspareunia is considered a predictor of decreased quality of sexual life, a major sexual disorder that should not be overlooked. Gynecological consultation should resolve concerns, identify the problem, and refer for professional sexual care if still needed.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Women’s sexual health improvement: sexual quality of life and pelvic floor muscle assessment in asymptomatic women

Baszak-Radomańska,

Wańczyk-Baszak,

Paszkowski

2024

Front. Med.

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“…The present study has the following limitations: (1) This study is a cross-sectional study and cannot reflect the causal effects between…”

Section: Limitationsmentioning

confidence: 93%

“…Depression is one of the most common psychiatric disorders characterized by persistent feelings of sadness, helplessness, hopelessness, reduced energy or fatigue, and considerable difficulty functioning in dealing with daily life ( 1 ). In the past decade, the prevalence of depression among young people has risen dramatically ( 2 ).…”

Section: Introductionmentioning

confidence: 99%

Immature defense mechanisms mediate the relationship between negative life events and depressive symptoms

Ma,

Cao,

Wei

et al. 2024

Front. Psychiatry

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ObjectiveThis study aimed to analyze the patterns of life events (LEs) and defense mechanisms in outpatients with depression and investigate the mediating role of defense mechanisms in the association between LEs and depressive symptoms in a psychosomatic outpatient sample in China.Materials and methodsAll of 2,747 outpatients (aged 18–65) from psychosomatic department were investigated in this study. LEs, depressive symptoms, and defense mechanisms were assessed by the Life Events Scale (LES), Patient-Health-Questionnaire-9 (PHQ-9), and the Defense Style Questionnaire (DSQ), respectively.ResultsBased on the optimal cut-off point of PHQ-9, 1840 (67.0%) patients had a PHQ-9 score of 10 or higher (depression group), and 907 (33.0%) had a score below 10 (non-depression group). The scores of Negative Life Events (NLEs), immature and intermediate defense mechanisms in the depression group were significantly higher than those in the non-depression group, while the scores of mature defense mechanisms were the opposite (p < 0.001). NLEs was directly related to depressive symptoms (b = 0.010, p < 0.001), and significant indirect effect via immature defense mechanisms (b = 0.008, p < 0.001) was observed.ConclusionImmature defense mechanisms play an important mediating role in the relationship between NLEs and depressive symptoms. Helping patients improving defense mechanisms and dealing with NLEs may be of great help in the treatment of relevant patients.

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“…Personalized medicine is an approach that tailors medical treatment to the individual patient’s needs based on their individual genetic makeup, lifestyle, and environment ( Ben-Akiva et al, 2023 ; U.S.P.S.T. Force et al, 2023 ).…”

Section: Future Perspectives and Challengesmentioning

confidence: 99%

Advances in the two-dimensional layer materials for cancer diagnosis and treatment: unique advantages beyond the microsphere

Zhang,

Yang,

et al. 2023

Front. Bioeng. Biotechnol.

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In recent years, two-dimensional (2D) layer materials have shown great potential in the field of cancer diagnosis and treatment due to their unique structural, electronic, and chemical properties. These non-spherical materials have attracted increasing attention around the world because of its widely used biological characteristics. The application of 2D layer materials like lamellar graphene, transition metal dichalcogenides (TMDs), and black phosphorus (BPs) and so on have been developed for CT/MRI imaging, serum biosensing, drug targeting delivery, photothermal therapy, and photodynamic therapy. These unique applications for tumor are due to the multi-variable synthesis of 2D materials and the structural characteristics of good ductility different from microsphere. Based on the above considerations, the application of 2D materials in cancer is mainly carried out in the following three aspects: 1) In terms of accurate and rapid screening of tumor patients, we will focus on the enrichment of serum markers and sensitive signal transformation of 2D materials; 2) The progress of 2D nanomaterials in tumor MRI and CT imaging was described by comparing the performance of traditional contrast agents; 3) In the most important aspect, we will focus on the progress of 2D materials in the field of precision drug delivery and collaborative therapy, such as photothermal ablation, sonodynamic therapy, chemokinetic therapy, etc. In summary, this review provides a comprehensive overview of the advances in the application of 2D layer materials for tumor diagnosis and treatment, and emphasizes the performance difference between 2D materials and other types of nanoparticles (mainly spherical). With further research and development, these multifunctional layer materials hold great promise in the prospects, and challenges of 2D materials development are discussed.

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Screening for Depression and Suicide Risk in Adults

Cited by 54 publications

References 55 publications

Women’s sexual health improvement: sexual quality of life and pelvic floor muscle assessment in asymptomatic women

Women’s sexual health improvement: sexual quality of life and pelvic floor muscle assessment in asymptomatic women

Immature defense mechanisms mediate the relationship between negative life events and depressive symptoms

Advances in the two-dimensional layer materials for cancer diagnosis and treatment: unique advantages beyond the microsphere

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