Screening for Cognitive Impairment in Multiple Sclerosis

Comparison of two brief neuropsychological batteries in people with multiple sclerosis

“…Some studies have reached similar conclusions, while a recently published paper did not. 21,23,27,30 We found that depressive symptoms (as assessed by CMDI Mood) had no influence on cognitive function. The CMDI, which isolates depressed mood from other symptoms often part of chronic diseases, gives a more realistic measure of depression in chronic diseases such as MS than other depression instruments.…”

Comparison of two brief neuropsychological batteries in people with multiple sclerosis

“…Some studies have reached similar conclusions, while a recently published paper did not. 21,23,27,30 We found that depressive symptoms (as assessed by CMDI Mood) had no influence on cognitive function. The CMDI, which isolates depressed mood from other symptoms often part of chronic diseases, gives a more realistic measure of depression in chronic diseases such as MS than other depression instruments.…”

Quality Improvement in Neurology

“…9 Sexual dysfunction symptoms are often overlooked in clinical evaluations of patients with MS. 9 Schairer et al 10 found that 12 Screening should start early, given the evidence that cognitive impairment may start early for patients with MS and appropriate referrals provided for potential positive results or changes with intervention. 12,13 The Mini-Mental State Examination was not included in the list of screening tools due to concerns that the tool is not sufficiently sensitive to detect the most common cognitive deficits seen in patients with MS. 14 Fatigue screening and follow-up for patients with MS captures the percentage of patients 18 years and older with diagnosis of MS who were screened for fatigue in past 12 months, and if screening positive, were provided appropriate follow-up. The desired outcome is to reduce or eliminate fatigue in patients with MS; however, as the cause of fatigue can be multifactorial, the immediate goal is to identify and address fatigue so the proper interventions can be undertaken/pursued.…”

“…12 Screening should start early, given the evidence that cognitive impairment may start early for patients with MS and appropriate referrals provided for potential positive results or changes with intervention. 12,13 The Mini-Mental State Examination was not included in the list of screening tools due to concerns that the tool is not sufficiently sensitive to detect the most common cognitive deficits seen in patients with MS. 14…”

The sensitivity of the Mini-Mental State Exam in the white matter dementia of multiple sclerosis

“…However, the basically subjective method of determining impairment is not sufficiently quantified for research purposes. In a study of cognitive impairment in multiple sclerosis, Beatty and Goodkin (1990) defined dementia as impairment with scores below the fifth percentile in three of the four cognitive areas that they measured. In this study, dementia was defined as follows: The 11 neuropsychological test scores were scored as discussed in the Neuropsychological Methods section.…”

Comparison of two brief neuropsychological batteries in people with multiple sclerosis

“…Some studies have reached similar conclusions, while a recently published paper did not. 21,23,27,30 We found that depressive symptoms (as assessed by CMDI Mood) had no influence on cognitive function. The CMDI, which isolates depressed mood from other symptoms often part of chronic diseases, gives a more realistic measure of depression in chronic diseases such as MS than other depression instruments.…”

Quality Improvement in Neurology

“…9 Sexual dysfunction symptoms are often overlooked in clinical evaluations of patients with MS. 9 Schairer et al 10 found that 12 Screening should start early, given the evidence that cognitive impairment may start early for patients with MS and appropriate referrals provided for potential positive results or changes with intervention. 12,13 The Mini-Mental State Examination was not included in the list of screening tools due to concerns that the tool is not sufficiently sensitive to detect the most common cognitive deficits seen in patients with MS. 14 Fatigue screening and follow-up for patients with MS captures the percentage of patients 18 years and older with diagnosis of MS who were screened for fatigue in past 12 months, and if screening positive, were provided appropriate follow-up. The desired outcome is to reduce or eliminate fatigue in patients with MS; however, as the cause of fatigue can be multifactorial, the immediate goal is to identify and address fatigue so the proper interventions can be undertaken/pursued.…”

“…12 Screening should start early, given the evidence that cognitive impairment may start early for patients with MS and appropriate referrals provided for potential positive results or changes with intervention. 12,13 The Mini-Mental State Examination was not included in the list of screening tools due to concerns that the tool is not sufficiently sensitive to detect the most common cognitive deficits seen in patients with MS. 14…”

The sensitivity of the Mini-Mental State Exam in the white matter dementia of multiple sclerosis

“…However, the basically subjective method of determining impairment is not sufficiently quantified for research purposes. In a study of cognitive impairment in multiple sclerosis, Beatty and Goodkin (1990) defined dementia as impairment with scores below the fifth percentile in three of the four cognitive areas that they measured. In this study, dementia was defined as follows: The 11 neuropsychological test scores were scored as discussed in the Neuropsychological Methods section.…”

Comparison of two brief neuropsychological batteries in people with multiple sclerosis

“…Some studies have reached similar conclusions, while a recently published paper did not. 21,23,27,30 We found that depressive symptoms (as assessed by CMDI Mood) had no influence on cognitive function. The CMDI, which isolates depressed mood from other symptoms often part of chronic diseases, gives a more realistic measure of depression in chronic diseases such as MS than other depression instruments.…”

Quality Improvement in Neurology

“…9 Sexual dysfunction symptoms are often overlooked in clinical evaluations of patients with MS. 9 Schairer et al 10 found that 12 Screening should start early, given the evidence that cognitive impairment may start early for patients with MS and appropriate referrals provided for potential positive results or changes with intervention. 12,13 The Mini-Mental State Examination was not included in the list of screening tools due to concerns that the tool is not sufficiently sensitive to detect the most common cognitive deficits seen in patients with MS. 14 Fatigue screening and follow-up for patients with MS captures the percentage of patients 18 years and older with diagnosis of MS who were screened for fatigue in past 12 months, and if screening positive, were provided appropriate follow-up. The desired outcome is to reduce or eliminate fatigue in patients with MS; however, as the cause of fatigue can be multifactorial, the immediate goal is to identify and address fatigue so the proper interventions can be undertaken/pursued.…”

“…12 Screening should start early, given the evidence that cognitive impairment may start early for patients with MS and appropriate referrals provided for potential positive results or changes with intervention. 12,13 The Mini-Mental State Examination was not included in the list of screening tools due to concerns that the tool is not sufficiently sensitive to detect the most common cognitive deficits seen in patients with MS. 14…”

The sensitivity of the Mini-Mental State Exam in the white matter dementia of multiple sclerosis

“…However, the basically subjective method of determining impairment is not sufficiently quantified for research purposes. In a study of cognitive impairment in multiple sclerosis, Beatty and Goodkin (1990) defined dementia as impairment with scores below the fifth percentile in three of the four cognitive areas that they measured. In this study, dementia was defined as follows: The 11 neuropsychological test scores were scored as discussed in the Neuropsychological Methods section.…”