Screening for Chlamydia and Gonorrhea

Abstract

Effect of low-normal vs high-normal oxygenation targets on organ dysfunction in critically ill patients: a randomized clinical trial. JAMA.

Underlying Reasons for Primary Care Visits Where Chlamydia Testing Was Performed in the United States, 2019 to 2022

“…Fifth, the AFC data had limited information on sex partners, men who have sex with men, or persons with nonbinary gender identity. The assessment of the reasons for clinic visits with chlamydia testing by those categories may be useful when USPSTF and CDC guidelines are reevaluated 11,12 . Sixth, because CPT codes do not have information related to anatomic site, we cannot distinguish whether patients had one chlamydia testing or multiple testing from multiple anatomic sites, especially for men who were with increased sexual behaviors of HIV infection.…”

“…The assessment of the reasons for clinic visits with chlamydia testing by those categories may be useful when USPSTF and CDC guidelines are reevaluated. 11,12 Sixth, because CPT codes do not have information related to anatomic site, we cannot distinguish whether patients had one chlamydia testing or multiple testing from multiple anatomic sites, especially for men who were with increased sexual behaviors of HIV infection. Seventh, our estimates may be affected by the COVID-19 pandemic status, especially at the early phase of the COVID pandemic when patients may have avoided or delayed visits, health care providers (especially for physician offices) may have seen fewer patients in their clinic practices than typical, or health care providers may have offered fewer preventive services.…”

A Machine Learning-Based Analytic Pipeline Applied to Clinical and Serum IgG Immunoproteome Data To Predict Chlamydia trachomatis Genital Tract Ascension and Incident Infection in Women

“…Repeated infections are common and may worsen disease. Noninvasive biomarkers for ascension of Ct to the upper female genital tract could serve as correlative endpoints for Ct vaccine efficacy in clinical trials, and biomarkers of enhanced risk of reinfection could identify individuals likely to benefit from increased screening to prevent sequelae ( 14 ). Previously, we found that the indirect effects of serum and cervical IgG against whole Ct reduced cervical Ct burden, a mediator for ascending infection, but their direct effects negated any protective role for IgG in prevention of Ct ascension ( 15 ).…”

Editorial on Screening for Chlamydia and Gonorrhea Corrected

“…The Editorial titled “Screening for Chlamydia and Gonorrhea,” published in the September 14, 2021, issue of JAMA , has been updated to fix the year of the initial USPSTF recommendation; wording in 3 other paragraphs; and the correct citation for reference 2. This article was corrected online.…”