Screening at Admission for Carrier Prevalence of Multidrug Resistant Organisms: A Hospital Based Observational Study

Abstract

"Relentless and dizzying rise of antimicrobial resistance"has contributed in a large measure to the persistence of infections as a major cause of morbidity and mortality.The purpose of this study was to catalog the carrier prevalence of MDR bacteria at the community level. It was mainly focused on isolating carriers from anterior nares and the gut and to determine their antimicrobial susceptibility pattern at admission. A total of 100 patients were screened for carriage prevalence of MDR bacteria in anterior nares and gut. Of the 158 isolates obtained from the stool samples, 48 (30.3%) were MDR, 34 (21.5%) were XDR and 3 (1.8%) were PDR. One more point worth noting was the pan-drug resistant organisms in the gut of 3 (03%) patients. 2 (66.6%) of these isolates were E.coli and the other was Enterococci. On the contrary, of 83 isolates obtained from nasal samples 18 (21.6%) were MDR and 7(8.43%) were XDR. (26.4%) of the Staphylococci obtained were multi-drug resistant. 20(29.4%) of the Staphylococci were MRSA. Of these 14 (70%) could be CA-MRSA. 33 (24.6%) and 30(22.3%) of the GNBs obtained from the stool samples were ESBL and MBL producers respectively.Thirteen (54.1%) of the isolates of Enterococci were multi-drug resistant. 10 (41.6%) of the Enterococci were resistant to vancomycin. In this situation, it is perhaps better for all the health care institutions to come up with their own screening strategy, in order to the curb the evolution of these multi-drug resistant bacteria to a destructive rate.