Screening and Preponderance of Peptic Ulcer and its Contributing Risk Factors Among Basrah City Residents in Iraq

Abstract

Background: With the recent widespread use of over- the- counter drugs, there has been a noticeable increase in the occurrence of gastrointestinal discomfort and peptic ulcer disease. However, peptic ulcer is a highly complex disorder resulting from an imbalance between gstricdestructive and protective factors. Objectives: To identifyrisk factors of peptic ulcer disease. Methods: This study was organized at Al-Basra teaching hospital and Al Sader teaching hospital in Basrah city, Iraq. Medical records and questionnaires filled by patients undergoing diagnostic and therapeutic upper gastrointestinal endoscopies following their gastric discomfort complaints. Information related to patients, disease history and medication history during six months prior to endoscopy procedures was collected. Results: A total of 476 patients were identified, including 246 (51.7%) patients with endoscopically diagnosed peptic ulcers and 230 (48.3%) patients without peptic ulcers. The population was predominately male and there were significant differences between age groups.Smoking correlated with a high relative risk;however, alcohol drinking had no significant role as a causative factor. The most extensively used drugs by patients who complained of peptic ulcers are NSAIDs, iron supplements, corticosteroids, and antiplatelet agents. A small number of patients weretreated for hypertension and diabetes, which were correlated with peptic ulcer risks. The presence of H-pylori infections was significantly associated with peptic ulcer diagnosis. Conclusion: The risk of peptic ulcer disease appeared to increase with chronic medication use and smoking, which aggravatethe contributing risk by H-pylori infections.

Instruction Program for Patient with Peptic Ulcer about Nutritional Habits: case-control study

“…A study conducted about screening and Preponderance of Peptic Ulcer and its Contributing Risk Factors Among Basrah City Residents in Iraq. Conclude there were a link between smoking and a higher risk of developing peptic ulcer disease, and that smoking increased the chance of H. pylori infections (13) .…”

Evaluation of IL-8 and IL-10 Levels in men with Irritable Bowel Syndrome

“…global prevalence estimated at 20% [4,5]. Irritable bowel syndrome is defined as a dysfunction of the colon, which leads to the appearance of symptoms in the digestive system, such as indigestion, bloating, constipation, and cramps that disappear after defecation; in addition to a feeling that the defecation is not completed after going to the bathroom, and sounds that the person close to the patient may hear [6,7]. There are many causes and factors that lead to irritable bowel syndrome.…”