Abstract:We have been developing low-field MRI of breast cancer using hyperpolarized contrast agents capable of interrogating metabolic pathways in vivo. While this five-year project has several objectives, the main areas of focus according to the approved Statement of Work for Year 1 were (i) design and development of second-generation xenon-129 automated polarizer, and (ii) optimization of preclinical low-field MRI system. Our team has designed the polarizer and, through a series of prototyping efforts, began xenon-1… Show more
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