Screening and analysis of 940 organic micro-pollutants in river sediments in Vietnam using an automated identification and quantification database system for GC–MS

Duong, Hanh Thi; Kadokami, Kiwao; Pan, Shuangye; Matsuura, Naoki; Nguyen, Trung Quang

doi:10.1016/j.chemosphere.2014.01.064

Cited by 77 publications

(28 citation statements)

References 46 publications

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“…GC coupled to tandem MS is a relatively new analytical technique which provides reliability and sensitivity for the trace analysis of environmental micropollutants including phthalates [32]. In the present improved method, nine phthalate esters (DMP, DEP, DBP, DHP, BBP, DBEP, DEHP, DNOP and DINP) were selected as model compounds, since they prove to be the most common phthalate contaminants in food and contact materials [25] and therefore, all of these phthalates should be included in the validated methods.…”

Section: Discussionmentioning

confidence: 99%

Improved method for rapid detection of phthalates in bottled water by gas chromatography–mass spectrometry

Otero

Saha

Moane

et al. 2015

Journal of Chromatography B

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Section: Discussionmentioning

confidence: 99%

Improved method for rapid detection of phthalates in bottled water by gas chromatography–mass spectrometry

Otero

Saha

Moane

et al. 2015

Journal of Chromatography B

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“…Each compound identified via the NIST 14 Library Search report has a corresponding mass spectrum showing the abundance of the possible numerous m/z peaks per compound (Ademiluyi et al, ; Duong, Kadokami, Pan, Matsuura, & Nguyen, ).…”

Section: Methodsmentioning

confidence: 99%

“…Prior to analysis, the MS was auto-tuned to perfluorotributylamine (PFTBA) using already established criteria to check the abundance of m/z 69, 219, 502 and other mechanism optimal and sensitivity conditions. Each compound identified via the NIST 14 Library Search report has a corresponding mass spectrum showing the abundance of the possible numerous m/z peaks per compound (Ademiluyi et al, 2016;Duong, Kadokami, Pan, Matsuura, & Nguyen, 2014).…”

Section: Gc-ms Quantification Of Alkaloid Constituentsmentioning

confidence: 99%

Alkaloid extracts from Bitter leaf ( Vernonia amygdalina ) and Black nightshade ( Solanum nigrum ) inhibit phosphodiesterase‐5, arginase activities and oxidative stress in rats penile tissue

et al. 2019

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The erectogenic potential of alkaloids extracted from Bitter leaf (Vernonia amygdalina) and Black nightshade (Solanum nigrum) was investigated in this study. Fresh leaves obtained from Bitter leaf and Black night shade were air‐dried, pulverized, and extracted for alkaloids. The inhibitory potential of the alkaloid extracts on arginase and phosphodiesterase‐5 (PDE‐5) activities in rats penile tissue was determined in vitro. The antioxidant properties were also evaluated and the constituent alkaloids quantified using GC‐MS. The alkaloid extracts inhibited arginase (0–30.51 μg/ml) and PDE‐5 (0–133.69 μg/ml) activities in a concentration‐dependent pattern. Similarly, the alkaloid extracts inhibited Fe2+‐induced lipid peroxidation in rats penile tissues, scavenged DPPH, OH, and NO radicals as a function of concentration. GC‐MS characterization revealed over 20 alkaloid compounds. The inhibition of PDE‐5‐, arginase‐, pro‐oxidant‐induced lipid peroxidative‐, and free radicals‐scavenging activities by the alkaloids is suggestive of putative mechanisms underlying their therapeutic use for managing erectile dysfunction in folklore medicine. Practical applications Alkaloids extracted from Black nightshade (Solanum nigrum) and Bitter leaf (Vernonia amygdalina) were characterized and investigated by standard procedures for inhibitory action against key erectile dysfunction‐linked enzymes and antioxidant activity. The alkaloids inhibited erectile dysfunction‐linked enzymes (arginase and PDE‐5) and showed considerable antioxidant activity in a concentration‐dependent manner. In view of this, we suggest the application of these results in the development of erectile dysfunction drugs in the pharmaceutical industry, with probable minimal or no adverse effect.

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“…Researchers have demonstrated the usefulness of using quantitative data for source identification [e.g. Pan et al (2014), Duong et al (2014), Bu et al (2009)]. However, qualitative data could usually be easily obtained than quantitative ones, especially in the high throughout screening analysis.…”

Section: Evaluation Of the Usefulness Of Qualitative Datamentioning

confidence: 99%

Screening for over 1000 organic micropollutants in surface water and sediments in the Liaohe River watershed

Luo

Wang

et al. 2015

Chemosphere

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h i g h l i g h t sThe reliability and usefulness of high throughout screening method was evaluated. The massive qualitative data help unveil pollution profiles among different sites. The semi-quantification results agree well with those from target analysis. The high throughout method is proven be a valuable tool in watershed management. a r t i c l e i n f o b s t r a c tHigh throughout screening method has gained attractive prospects because it offers a fast and effective approach to obtain a holistic picture of organic micropollutant (OM) pollution in a site specific environment. However, reliability and usefulness of the generated data sets for OM pollution profiles and occurrence levels have not been fully evaluated. In this paper, we screened 1030 OMs in surface water and sediments from the selected rivers of the Liaohe River watershed to (1) examine the usefulness of using qualitative data to gain insights into source identification and (2) further evaluate the reliability of the semi-quantification results in a filed study. The results showed that 81 and 89 OMs at concentrations up to 5670 ng/L and 6714 ng/g were identified in surface water and sediments, respectively. Qualitative data could be used to identify the similarity (or dissimilarity) of pollution sources at different locations for surface water, which could provide insights for source back tracking of water contamination. Accuracy tests showed that our semi-quantification results agree well with those from previously reported values and our target analysis. Though our results for the majority of newly quantified OMs need to be further confirmed, we have demonstrated that this method is suitable for understanding the pollution characteristics and occurrence levels of OMs in the environment for environmental scientists and managers.

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Screening and analysis of 940 organic micro-pollutants in river sediments in Vietnam using an automated identification and quantification database system for GC–MS

Cited by 77 publications

References 46 publications

Improved method for rapid detection of phthalates in bottled water by gas chromatography–mass spectrometry

Improved method for rapid detection of phthalates in bottled water by gas chromatography–mass spectrometry

Alkaloid extracts from Bitter leaf ( Vernonia amygdalina ) and Black nightshade ( Solanum nigrum ) inhibit phosphodiesterase‐5, arginase activities and oxidative stress in rats penile tissue

Screening for over 1000 organic micropollutants in surface water and sediments in the Liaohe River watershed

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