Screen printed carbon electrode modified with magnetic core shell manganese ferrite nanoparticles for electrochemical detection of amlodipine

Abstract

In the present work, a rapid and sensitive detection of the amlodipine (AML) based on the modified screen printed carbon electrode (SPCE) is developed. At first, SPCE was modified with magnetic core shell manganese ferrite nanoparticles (MCSNP). Cyclic voltammetry (CV) was used to study the electrochemical behaviour of AML and its determination was conducted by applying differential pulse voltammetry (DPV). The results were showed that, the modified SPCE in comparison with unmodified SPCE exhibited the enhanced electrocatalytic activity toward the oxidation of AML. A single irreversible oxidation peak was observed at a potentials of 600 and 725 mV (on the scale of Ag/AgCl electrode) on the modified SPCE and unmodified SPCE, respectively. Under the optimized conditions, the anodic peak current of AML recorded by DPV varies linearly with AML concentration in the range 0.5-400 µM with a detection limit of 0.1 µM. The modified SPCE was used for the quantitative analysis of AML in AML tablet and urine samples and the results indicated the feasibility of the developed method for AML analysis in routine detection.

Hybrid Nanostructure Composed of Homogeneously Decorated MoS2 Nanosheets on Graphene for Simultaneous Electrochemical Determination of Amlodipine and Hydrochlorothiazide

“…28 Two peaks appear at 32°and 57°can be well indexed to (100) and ( 110 I, this value is comparable to the values declared in some previous papers for AML electrochemical oxidation at the surface of different chemically modified electrodes. 18,[41][42][43][44][45] Figure 3 shows the cyclic voltammograms obtained in a 200.0 μM AML solution (voltammogram a with an unmodified SPCE and voltammogram b with the MoS 2 NSs-G/SPCE). The highest oxidation peak potential of AML has been observed at 620 mV for MoS 2 NSs-G/SPCE, which 120 mV more negative in comparison with the signal corresponding to the unmodified SPCE.…”

Simultaneous Determination of Doxorubicin and Dasatinib by using Screen-Printed Electrode/Ni–Fe Layered Double Hydroxide

“…However, the direct electron transfer of analytes is slow on the surface of a bare electrode, leading to improper sensitivity and limit of detection. ,− The modification of an electrode surface can enhance the activity of electrochemical sensors with acceptable recovery rates. ,− Numerous studies have been conducted for the improvement of electrochemical sensing capabilities using diverse nanomaterials. − …”

Synergetic effects of a poly-tartrazine/CTAB modified carbon paste electrode sensor towards simultaneous and interference-free determination of benzenediol isomers

“…[12][13][14] Additionally, electrochemical sensors are well-suited for simultaneously detecting multiple analytes and on-site detection, and can be integrated with robust, portable, or miniaturized devices for targeted experiments in clinical and diagnostic applications. [15][16][17][18][19][20] Electrode modification is a key area of interest, enabling the alteration of electrochemical properties using various materials. Modified electrodes have shown promise in detecting substances at low concentrations.…”

“…12–14 Additionally, electrochemical sensors are well-suited for simultaneously detecting multiple analytes and on-site detection, and can be integrated with robust, portable, or miniaturized devices for targeted experiments in clinical and diagnostic applications. 15–20…”