Screen Failures in Clinical Trials in Retina

Hasan, Nasiq; Mehrotra, Kunaal; Danzig, Carl J.; Eichenbaum, David A.; Ewald, Amy; Regillo, Carl; Momenaei, Bita; Sheth, Veeral S.; Lally, David R.; Chhablani, Jay

doi:10.1016/j.oret.2024.05.014

Ophthalmology Retina

2024

DOI: 10.1016/j.oret.2024.05.014

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Screen Failures in Clinical Trials in Retina

Nasiq Hasan,

Kunaal Mehrotra,

Carl J. Danzig

et al.

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2024

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Cited by 1 publication

References 26 publications

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Photobiomodulation use in ophthalmology – an overview of translational research from bench to bedside

Valter,

Tedford,

Eells

et al. 2024

Front. Ophthalmol.

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Photobiomodulation (PBM) refers to the process in which wavelengths of light are absorbed by intracellular photoacceptors, resulting in the activation of signaling pathways that culminate in biological changes within the cell. PBM is the result of low-intensity light-induced reactions in the cell in contrast to thermal photoablation produced by high-intensity lasers. PBM has been effectively used in the clinic to enhance wound healing and mitigate pain and inflammation in musculoskeletal conditions, sports injury, and dental applications for many decades. In the past 20 years, experimental evidence has shown the benefit of PBM in increasing numbers of retinal and ophthalmic conditions. More recently, preclinical findings in ocular models have been translated to the clinic with promising results. This review discusses the preclinical and clinical evidence of the effects of PBM in ophthalmology and provides recommendations of the clinical use of PBM in the management of ocular conditions.

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Photobiomodulation use in ophthalmology – an overview of translational research from bench to bedside

Valter,

Tedford,

Eells

et al. 2024

Front. Ophthalmol.

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show abstract

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Screen Failures in Clinical Trials in Retina

Cited by 1 publication

References 26 publications

Photobiomodulation use in ophthalmology – an overview of translational research from bench to bedside

Photobiomodulation use in ophthalmology – an overview of translational research from bench to bedside

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