2012
DOI: 10.1590/s0100-736x2012001200004
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Scrapie e seu diagnóstico diferencial em ovinos no Mato Grosso do Sul

Abstract: Pesq. Vet. Bras. 32(12):1230-1238, dezembro 2012 1230 RESUMO.-Scrapie é uma doença infecciosa, neurodegenerativa fatal, causada pelo príon scrapie (PrP sc ). Apresenta-se tanto na forma clássica em ovinos e caprinos geneticamente susceptíveis quanto na forma atípica em ovinos. A primeira notiϐicação oϐicial do Brasil à Organização Mundial de Saú-Scrapie e seu diagnóstico diferencial em ovinos no Mato Grosso do Sul

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Cited by 2 publications
(3 citation statements)
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(38 reference statements)
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“…As described in other outbreaks in Brazil and the world, the disease occurred without an apparent macroscopic lesion. Loss of wool and weight can be related but are not characteristic of the disease (MARTINS et al, 2012;ESTEVES et al, 2021). Histological lesions in classic scrapie are at the brain stem (obex), characteristic of vacuolization of neurons and neuropil without inflammatory reaction, as described in this study.…”
Section: Discussionsupporting
confidence: 48%
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“…As described in other outbreaks in Brazil and the world, the disease occurred without an apparent macroscopic lesion. Loss of wool and weight can be related but are not characteristic of the disease (MARTINS et al, 2012;ESTEVES et al, 2021). Histological lesions in classic scrapie are at the brain stem (obex), characteristic of vacuolization of neurons and neuropil without inflammatory reaction, as described in this study.…”
Section: Discussionsupporting
confidence: 48%
“…Importantly, only one animal in this outbreak, had characteristic lesions in the obex. This intensity is uncommon, as usually the animals have very characteristic and evident neuronal or neuropil vacuolization in the obex in outbreaks, as observed in some studies in Brazil (MARTINS et al, 2012;ANDRADE et al, 2015). Fourteen sheep were positive by the IHC in the lymphoid tissues, however, only two animals that were positive for IHC in the obex.…”
Section: Discussionmentioning
confidence: 80%
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