Warthin‐Finkeldey giant cells—A useful clue for the cytodiagnosis of Kimura disease: A report of three cases

Abstract

Kimura disease (KD) is a rare, idiopathic chronic inflammatory disorder that usually presents as unilateral painless lymphadenopathy or soft tissue swelling of the head and neck region in young Asian males. The disease lacks pathognomonic clinical and cytomorphological features and can be mistaken for many reactive and malignant conditions. We report three cases of KD presenting as bilateral swelling of the head and neck region, and describe the cytomorphological features of each. In the correct clinical setting, a polymorphous lymphoid aspirate with eosinophils and Warthin‐Finkeldey giant cells should raise a suspicion of KD and prompt further work up.

Kimura disease forming a human polyomavirus 6–negative parotid gland nodule with prominent squamous metaplasia in a young female: A case report

“…As a diagnostic modality for KD, FNAC may contribute to its diagnosis. A histological evaluation may be omitted if FNAC confirms polymorphous lymphoid cells with eosinophils and Warthin–Finkeldey cells [10 , 11] . In our case, FNAC was not diagnostic for KD due to the lack of eosinophils and Warthin–Finkeldey cells; the samples obtained by FNAC likely represented reactive lymphoid follicles.…”