T1 and FLAIR signal intensities are related to tau pathology in dominantly inherited Alzheimer disease
Farzaneh Rahmani,
Matthew R. Brier,
Brian A. Gordon
et al.
Abstract:Carriers of mutations responsible for dominantly inherited Alzheimer disease provide a unique opportunity to study potential imaging biomarkers. Biomarkers based on routinely acquired clinical MR images, could supplement the extant invasive or logistically challenging) biomarker studies. We used 1104 longitudinal MR, 324 amyloid beta, and 87 tau positron emission tomography imaging sessions from 525 participants enrolled in the Dominantly Inherited Alzheimer Network Observational Study to extract novel imaging… Show more
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