<scp>R</scp>osai <scp>D</scp>orfman disease diagnosed by fine‐needle aspiration cytology in a young man with <scp>HIV</scp> infection

Sall, Abibatou; Touré, Awa Oumar; Ndiaye, Fatou Samba Diago; Sène, Abdoulaye; Sall, Fatimata Bintou; Faye, Blaise Felix; Seck, Moussa; Diop, Saliou

doi:10.1002/ccr3.391

Cited by 12 publications

(12 citation statements)

References 16 publications

(22 reference statements)

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“…Cytology is virtually diagnostic of this self-limited disease. 14 The exact etiology of RDD is not known. Various viruses like Human Herpes virus 6, Epstein -Barr virus and recently, polyoma virus were implicated in the causation, but none were proven.…”

Section: Resultsmentioning

confidence: 99%

“…Various viruses like Human Herpes virus 6, Epstein -Barr virus and recently, polyoma virus were implicated in the causation, but none were proven. 14 The diagnosis of most inflammatory breast lesions is clinical and usually resolve within a short period. However, rare chronic inflammatory lesions and reactive lesions like RDD with their atypical presentations cause diagnostic dilemmas.…”

Section: Resultsmentioning

confidence: 99%

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Utility of Fnac in Uncommon Inflammatory and Reactive Lesions of Breast: An Unsuspected Clinical Scenario

Rajyalakshmi¹,

Akhtar²,

Bhaskar³

et al. 2018

jebmh

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BACKGROUND Fine Needle Aspiration Cytology (FNAC) has become an invaluable tool in the preoperative evaluation of the breast lumps and is a part of initial screening by triple assessment approach. Its main purpose is to differentiate benign lesions from malignant lesions. However inflammatory lesions of the breast are relatively uncommon benign breast lesions and can be of an abnormal finding on imaging. These lesions form palpable lumps and simulate a malignant process, both clinically and radiologically. Core biopsies may not help in the diagnosis of inflammatory lesions and are not necessary in most of these cases. Here, the present study aims to highlight the importance of FNAC in the diagnosis of inflammatory lesions of the breast. MATERIALS AND METHODS The present study was a prospective study conducted in Government General Hospital, Rangaraya Medical College, Kakinada, for a period of one year from July 2017 to June 2018. A total number of 591 female patients with palpable breast lumps were subjected to FNAC. Ten cases out of 591 were showed clinical and radiological discrepancies. Aspirated smears were studied microscopically, and final diagnosis was made after assessment by two pathologists. All ten cases were followed up for six months to assess the response to therapy.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Utility of Fnac in Uncommon Inflammatory and Reactive Lesions of Breast: An Unsuspected Clinical Scenario

Rajyalakshmi¹,

Akhtar²,

Bhaskar³

et al. 2018

jebmh

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“…RDD is a well-defined clinicopathological entity, first described by Destombes in 1965 [ 1 , 5 ]. Later in 1969, Juan Rosai and Ronald Dorfman, recognized it as a distinct disease entity comprising sinus histiocytosis and massive lymphadenopathy [ 5 , 6 ]. 20–50% of RDD patients with nodal/cutaneous disease undergo spontaneous remission [ 2 ].…”

Section: Discussionmentioning

confidence: 99%

ROSE in Rosai–Dorfman–Destombes (RDD) disease: a cytological diagnosis

et al. 2021

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Background Rosai–Dorfman–Destombes (RDD) is also known as sinus histiocytosis with massive lymphadenopathy (SHML). It is a benign proliferative disorder of histiocytes, affecting lymph nodes, rarely with extra-nodal involvement. Rapid on-site evaluation (ROSE) with fine-needle aspiration cytology (FNAC) can be utilized as a minimally invasive investigation to avoid unnecessary surgery of this self-limiting disease. Case presentation A 65-year-old female presented with complaints of bilateral cervical lymphadenopathy since 1 year. Rapid on-site stain with FNAC from bilateral cervical lymph nodes revealed features of Rosai–Dorfman–Destombes (RDD) disease. Conclusion FNAC with rapid on-site evaluation can provide a simple and cost-effective method for looking at the unique cytological features of the disease and act as a first-line investigation.

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“…4 The prevalence is estimated at 1:200 000, affecting children and young adults most commonly, with an unclear pathogenesis although recent evidence has suggested a viral stimulus, including Epstein Barr virus, HIV, or cytomegalovirus (CMV). 8 Classically, RDD presents nodally, with 43% presenting extranodally, and may present over months to years like other forms of non-LCH. 4 Patients typically have bilateral, massive, painless cervical lymphadenopathy, multisystem involvement, including the skin, bone, and gastrointestine (GI), although CNS involvement is less common.…”

Section: Discussionmentioning

confidence: 99%

Rosai-Dorfman Disease: A Less Common Cause of Leptomeningeal and Nerve Root Enhancement

Petraglia

Davick

Mandell

et al. 2020

The Neurohospitalist

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A 46-year-old male experienced progressive neurocognitive decline, weight loss, intermittent headaches, and weakness over 6 months. Magnetic resonance imaging of the brain revealed hydrocephalus and the spinal cord imaging showed diffuse leptomeningeal enhancement with prominent nerve root involvement. Intradural biopsy of lumbar arachnoid tissue found mixed inflammatory infiltrate consisting predominantly of histiocytes, S100 and CD68 positivity, and lymphocytophagocytosis (emperipolesis) consistent with extranodal Rosai-Dorfman disease. Rosai-Dorfman disease, a non-Langerhans cell histocytic disorder, can mimic the appearance of neurosarcoidosis and leptomeningeal carcinomatosis and should remain on the differential of a patient presenting with diffuse leptomeningeal enhancement, a common occurrence on a neurohospitalist service.

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Rosai Dorfman disease diagnosed by fine‐needle aspiration cytology in a young man with HIV infection

Abstract: Key Clinical MessageRDD (Rosai Dorfman disease) is a rare and benign histiocytic proliferative disorder of unknown etiology. FNAC (Fine-needle aspiration cytology) is a useful and reliable tool for the diagnosis of RDD, and as such, biopsy is avoidable.

Cited by 12 publications

References 16 publications

Utility of Fnac in Uncommon Inflammatory and Reactive Lesions of Breast: An Unsuspected Clinical Scenario

Utility of Fnac in Uncommon Inflammatory and Reactive Lesions of Breast: An Unsuspected Clinical Scenario

ROSE in Rosai–Dorfman–Destombes (RDD) disease: a cytological diagnosis

Rosai-Dorfman Disease: A Less Common Cause of Leptomeningeal and Nerve Root Enhancement

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