PEITC Induces DNA Damage and Inhibits DNA Repair‐Associated Proteins in Human Retinoblastoma Cells In Vitro
Sheng‐Yao Hsu,
Yi‐Ping Huang,
Te‐Chun Hsia
et al.
Abstract:Phenethyl isothiocyanate (PEITC), a natural product, exists in biological activities, including anticancer activity in many human cancer cells. No information shows that PEITC affects DNA damage in human retinoblastoma (RB) cells in vitro. In this study, the aim of experiments was to determine whether PEITC decreased total viable cell number or not by inducing protein expressions involved in DNA damage and repair in Y79 RB cells in vitro. Total cell viability was measured by PI exclusion assay, and PEITC reduc… Show more
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