PEG‐45/dodecyl glycol co‐polymer and bis‐diglyceryl polyacyladipate‐2: Two culprits responsible of an allergic contact dermatitis to a lip balm

Allergic contact dermatitis caused by PEG‐22 and PEG‐45 dodecyl glycol copolymers in two skin‐repairing creams

“…Only one case of ACD from PEG‐22/dodecyl glycol copolymer in the same skin‐repairing cream from PEG‐45/dodecyl copolymer in a lip balm have been published to date 2,3 . Our case seems to suggest the possibility of cross‐reactivity between PEG‐22 and PEG‐45 dodecyl glycol copolymers 3 .…”

“…Copolymers are widely used in cosmetics, because of their antistatic, film‐forming, binding, suspending, viscosity‐increasing, skin‐conditioning and emulsion‐stabilising properties 1 . There are many different co‐polymers; however, since the review published by Quartier et al in 2006, 1 only a few additional reports of ACD from different copolymers have been published 2,3 . The sensitising capacities of copolymers have probably been underestimated because of their high molecular weight and the exact nature of the haptens is still unknown 1,3 …”

“…1 There are many different copolymers; however, since the review published by Quartier et al in 2006, 1 only a few additional reports of ACD from different copolymers have been published. 2,3 The sensitising capacities of copolymers have probably been underestimated because of their high molecular weight and the exact nature of the haptens is still unknown. 1,3 Only one case of ACD from PEG-22/dodecyl glycol copolymer in the same skin-repairing cream from PEG-45/dodecyl copolymer in a lip balm have been published to date.…”

“…2,3 The sensitising capacities of copolymers have probably been underestimated because of their high molecular weight and the exact nature of the haptens is still unknown. 1,3 Only one case of ACD from PEG-22/dodecyl glycol copolymer in the same skin-repairing cream from PEG-45/dodecyl copolymer in a lip balm have been published to date. 2,3 Our case seems to suggest the possibility of cross-reactivity between PEG-22 and PEG-45 dodecyl glycol copolymers.…”

“…1,3 Only one case of ACD from PEG-22/dodecyl glycol copolymer in the same skin-repairing cream from PEG-45/dodecyl copolymer in a lip balm have been published to date. 2,3 Our case seems to suggest the possibility of cross-reactivity between PEG-22 and PEG-45 dodecyl glycol copolymers. 3 Indeed, in the previously published case, 2 the hypothesis of primary sensitisation to PEG-22/dodecyl glycol copolymer can be raised in view of the rather long delay in onset of the first episode of ACD in our patient.…”