A comparison of the He1 photoelectron (PE) spectra of some androstanones and adrostenones with those of the corresponding parent hydrocarbon androstane reveals that, in the gas phase, the electronic effect of the substituent depends strongly on whether the ring A is or is not conformationally fixed. This result is of especial interest because several postulated mechanisms of long-range effects do exist and because fast intramolecular electron transfer (ET) has been observed in steroid solutions.