OTULIN's influence on neuroinflammation and pain modulation in trigeminal neuralgia
Haiyang Wang,
Heng Wang,
Wenhao Zheng
et al.
Abstract:IntroductionTrigeminal neuralgia (TN), marked by chronic pain from neural damage, is closely associated with inflammation. The role of OTULIN, a key regulator in inflammation and autophagy, is not fully understood in TN. The regulatory mechanism of OTULIN, a key protein involved in modulating inflammatory responses and autophagy processes, remains incompletely elucidated, particularly in the context of TN and neuroinflammation.MethodsAn infraorbital nerve ligation‐induced rat model of TN was used. OTULIN's exp… Show more
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