Abstract:Objectives: To assess if angiogenic factors could improve first-trimester screening for the prediction of fetal growth restriction (FGR). Methods: A nested case control study drawn from a prospective first trimester cohort (2007)(2008)(2009)(2010)(2011)(2012). The outcome was the development of FGR (birthweight <10th centile with Doppler abnormalities). Logistic regression-based predictive models were developed for the prediction of early and late FGR, subdivided for abnormalities of umbilical artery. The mode… Show more
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