MIF as a potential diagnostic and prognostic biomarker for triple‐negative breast cancer that correlates with the polarization of M2 macrophages
Mengting Chen,
Hongsen Liu,
Bo Hong
et al.
Abstract:Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine that plays a crucial role in antitumor immunity. However, the role of MIF in influencing the tumor microenvironment (TME) and prognosis of triple‐negative breast cancer (TNBC) remains to be elucidated. Using R, we analyzed single‐cell RNA sequencing (scRNA‐seq) data of 41 567 cells from 10 TNBC tumor samples and spatial transcriptomic data from two patients. Relationships between MIF expression and immune cell infiltration, clinicopatho… Show more
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