LncRNA 152 attenuates lipopolysaccharide‐induced acute kidney injury in rats by regulating the FGF23/Klotho/MAPK axis
Li Lei,
Sheng Zhang,
Rui Hou
et al.
Abstract:AimThis study aimed to explore the effect and related mechanisms of LncRNA 152 in acute kidney injury (AKI).MethodsQRT‐PCR was used to detect the expression of LncRNA 152, FGF23 and Klotho in the serum of patients with AKI. Subsequently, Sprague Dawley (SD) rats were induced into AKI animal model by lipopolysaccharide (LPS). Then, H&E staining was performed to observe the pathological changes in the rat kidney tissues; qRT‐PCR to detect the expression of LncRNA 152, FGF23 and Klotho in the rat kidney tissu… Show more
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