<scp><i>Acmella oleracea</i></scp> extract increases collagen content and organization in partially transected tendons

Moro, Selma Delgado de Souza; Fujii, Lucas de Oliveira; Teodoro, Luís Felipe Rodrigues; Frauz, Katleen; Mazoni, Alysson Fernandes; Esquisatto, Marcelo Augusto Marretto; Rodrigues, Rodney Alexandre Ferreira; Pimentel, Edson Rosa; Aro, Andréa Aparecida de

doi:10.1002/jemt.23809

Cited by 3 publications

(2 citation statements)

References 72 publications

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“…Interestingly, Acmella oleracea may also favor tendon repair, via increasing the molecular organization and content of collagen in partially transected tendons. 138 Whether this effect help restore the impaired ECM in aged skin needs further studies.…”

Section: Promising Naturally Derived Ingredients From An Anti-ageing ...mentioning

confidence: 99%

Skin Ageing: A Progressive, Multi-Factorial Condition Demanding an Integrated, Multilayer-Targeted Remedy

Liang¹,

Su²,

Wang³

2023

CCID

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Of the human organs, skin is the most visible one that displays the manifestations of ageing. It has a very intricate microanatomical structure and performs several key physiological functions. The pathophysiology of cutaneous ageing is characterized by deterioration of structural stability and functional integrity, implying a continuous reduction in maximal function and reserve capacity, as a result of the accumulating damage due to both intrinsic and extrinsic factors. Elimination of unfavorable expressions associated with facial and cutaneous ageing is the key patient demand in aesthetic dermatology. Even though the progress has been made in nonsurgical therapies like fillers and lasers, non-invasive interventions by using skin care products designed for rejuvenation at an early stage are the most popular and accessible solution among people. In this review, we have scrutinized the ageing-associated cutaneous changes at molecular, cellular and tissue levels. To optimize the ageing process towards a healthy skin, we propose an integrated, multilayer-targeted intervention, which involves both topical application of anti-ageing formulations from outside and oral supplementation from inside. Additionally, several promising naturally derived ingredients are reviewed from an anti-aging perspective. Most of them possess various bioactivities and may contribute to the development of the mentioned anti-ageing remedy.

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Section: Promising Naturally Derived Ingredients From An Anti-ageing ...mentioning

confidence: 99%

Skin Ageing: A Progressive, Multi-Factorial Condition Demanding an Integrated, Multilayer-Targeted Remedy

Liang¹,

Su²,

Wang³

2023

CCID

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“…Yamane et al showed that jambù helped in collagen deposition and decreased the time of the healing process [ 61 ]. Moreover, de Souza Moro et al demonstrated that A. oleracea increased the molecular organization and content of collagen [ 103 ].…”

Section: Biological Activitiesmentioning

confidence: 99%

A Review of the Chemistry and Biological Activities of Acmella oleracea (“jambù”, Asteraceae), with a View to the Development of Bioinsecticides and Acaricides

Ferrati

Baldassarri

Cappellacci

et al. 2022

Plants

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Human pathologies, environmental pollution, and resistance phenomena caused by the intensive use of chemical pesticides have shifted the attention of the agrochemical industries towards eco-friendly insecticides and acaricides. Acmella oleracea (L.) R. K. Jansen (jambù) is a plant native to South America, widely distributed and cultivated in many countries due to its numerous pharmacological properties. This review analyzes literature about the plant, its uses, and current knowledge regarding insecticidal and acaricidal activity. Acmella oleracea has proven to be a potential pesticide candidate against several key arthropod pest and vector species. This property is inherent to its essential oil and plant extract, which contain spilanthol, the main representative of N-alkylamides. As a result, there is a scientific basis for the industrial exploitation of jambù in the preparation of green insecticides. However, studies related to its toxicity towards non-target species and those aimed at formulating and developing marketable products are lacking.

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A Single-Center Study Evaluating the Effects of a Topical Serum Combining Postbiotics, Peptides, and Botanical Extracts on Skin

Few¹,

Lee²,

Semersky³

et al. 2023

Aesthetic Surgery Journal Open Forum

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Background Aging, influenced by intrinsic and extrinsic factors, leads to visible skin changes such as dryness, surface roughness, and loss of luminosity. Proper skin care can mitigate some of these effects, with topical combination products offering support through complementary mechanisms. Objectives To test efficacy and safety of GSYBS-7 (Goop Beauty Youth-Boost Peptide Serum [Goop, Inc; Santa Monica, CA]), a topical postbiotic and botanical combination serum, used twice daily on facial skin for 6 weeks. Methods In this 19-patient pilot study, the primary efficacy measure was improvement on the Global Ranking Scale (GRS) at 42 days. A 12-point patient satisfaction survey and the serum’s effect on healing after ablative laser treatment served as secondary and exploratory measures, respectively. Results Statistically significant improvements in all GRS domains were observed as early as day 7 with ongoing improvement up to day 42. A > 1-point improvement was observed for dehydration (1.8; 95% CI, 1.5-2.2), visible pores (1.6; 95% CI, 1.3-2.0), surface roughness (1.6; 95% CI, 1.3-1.9), imbalance (1.3; 95% CI, 0.9-1.7), static wrinkles (1.3; 95% CI, 0.9-1.6), pigmentation (1.3; 95% CI, 1.0-1.5), and vasculature (1.2; 95% CI, 0.8-1.5). Independent photographic review and patient satisfaction surveys corroborated these findings. At day 42, 94.4% of patients were very satisfied with the results, and 88.9% would recommend GSYBS-7 to family and friends. No adverse events were reported and 100% of patients indicated that GSYBS-7 was gentle enough for everyday use. Conclusions GSYBS-7 appears to be an effective and well-tolerated combination topical for the management of age-related and environment-induced skin changes.

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Acmella oleracea extract increases collagen content and organization in partially transected tendons

Cited by 3 publications

References 72 publications

Skin Ageing: A Progressive, Multi-Factorial Condition Demanding an Integrated, Multilayer-Targeted Remedy

Skin Ageing: A Progressive, Multi-Factorial Condition Demanding an Integrated, Multilayer-Targeted Remedy

A Review of the Chemistry and Biological Activities of Acmella oleracea (“jambù”, Asteraceae), with a View to the Development of Bioinsecticides and Acaricides

A Single-Center Study Evaluating the Effects of a Topical Serum Combining Postbiotics, Peptides, and Botanical Extracts on Skin

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