H₂Sand Bioinorganic Metal Complexes

Effect of Metal Coordination Environment on the Stability of Zinc Complexes and Their Reactivity with NaSH

“…With nitric oxide (NO) and carbon monoxide (CO) it belongs to the family of the "gasotransmitters". [1][2][3] Whereas the chemical biology of NO and CO has been well studied, this is much less so for H 2 S. Among the cellular targets of H 2 S, the transition metals constitute the more common sites of attack as they easily react with the Lewis-base sulfur of H 2 S. [4][5][6][7][8][9][10][11] More recent studies revealed signaling pathways involving metalloproteins. [12][13][14][15][16] In this context, motivated by our aim of clarifying the reactions H 2 S is involved in, our studies on the coordination of H 2 S to transition metals started a few years ago and focused both on properly tailored low molecular weight metal complexes and on natural metalloproteins.…”

Unequivocal Characterization of an Osmium Complex with a Terminal Sulfide Ligand and Its Transformation into Hydrosulfide and Methylsulfide

“…Metal sulfides have attracted great attention in recent years. The interest is mainly motivated by the relevance of these types of compounds in biological systems and by the role they can play in the metal-catalyzed hydrodesulfurization of fossil fuels . Sulfur is larger and softer than oxygen.…”