Guillain‐Barre syndrome secondary to COVID‐19 infection: A case report

Abstract

Guillain‐Barre syndrome (GBS) is a rare autoimmune disease that often manifests as a post‐viral complication. However, its association with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is unclear. We present a rare case of GBS secondary to COVID‐19 infection complicated by rapidly progressive sensorimotor deterioration resistant to plasma exchange therapy.

Guillain–Barre syndrome with pleocytosis requires workup for cerebral disease

“…Letter to the editor, With interest we read the article by Tran et al on a 60-year-old-male who developed progressive, ascending muscle weakness and sensory disturbances of the upper and limbs 3 days after having been tested positive for SARS-CoV-2. 1 COVID-19 took a mild course and manifested only with nausea, fever, and myalgias. 1 The patient was diagnosed with Guillain-Barre syndrome (GBS), subtype acute, motor and sensory, axonal neuropathy (AMSAN) an was treated with steroids and plasmaphereseis (PLEX).…”

“…1 COVID-19 took a mild course and manifested only with nausea, fever, and myalgias. 1 The patient was diagnosed with Guillain-Barre syndrome (GBS), subtype acute, motor and sensory, axonal neuropathy (AMSAN) an was treated with steroids and plasmaphereseis (PLEX). 1 Despite these measures, the patient deteriorated and developed quadriplegia, respiratory insufficiency, respiratory distress syndrome (ARDS) requiring intubation and mechanical ventilation, and septic shock.…”

“…1 The patient was diagnosed with Guillain-Barre syndrome (GBS), subtype acute, motor and sensory, axonal neuropathy (AMSAN) an was treated with steroids and plasmaphereseis (PLEX). 1 Despite these measures, the patient deteriorated and developed quadriplegia, respiratory insufficiency, respiratory distress syndrome (ARDS) requiring intubation and mechanical ventilation, and septic shock. 1 The patient was lastly transferred to a long-term acute care hospital for continued management and ventilator weaning.…”

“…1 Despite these measures, the patient deteriorated and developed quadriplegia, respiratory insufficiency, respiratory distress syndrome (ARDS) requiring intubation and mechanical ventilation, and septic shock. 1 The patient was lastly transferred to a long-term acute care hospital for continued management and ventilator weaning. 1 The study is compelling, but has limitations that are cause of concerns and should be discussed.…”

“…1 The patient was lastly transferred to a long-term acute care hospital for continued management and ventilator weaning. 1 The study is compelling, but has limitations that are cause of concerns and should be discussed.…”