DRESS syndrome in a patient undergoing stem cell transplantation: Can sirolimus be involved?
Fortunato Cassalia,
Alice Spiller,
Roberto Salmaso
et al.
Abstract:We present a case of sirolimus‐induced drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome in a stem cell transplant patient. Sirolimus is an immunosuppressive drug that inhibits the mammalian target of rapamycin (mTOR) pathway. A 24‐year‐old male with a history of acute lymphoblastic leukemia (ALL) underwent testicular extraction followed by hematopoietic stem cell transplantation (HSCT). He presented with pruritic eczematous lesions, which were initially treated with topical steroids. Howe… Show more
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