DPM2 serve as novel oncogene and prognostic marker transactivated by ESR1 in breast cancer
Jiahao Lu,
Yuejiao Feng,
Yiting Zhou
et al.
Abstract:Breast cancer (BRCA) is the most common malignancies worldwide with increasing rate. Dolichol phosphate mannose synthase (DPMS) is a critical mannosyltransferase involved in the posttranslational modification of proteins. At present, there is limited knowledge regarding the function of DPMS in breast cancer. In this study, silica analysis in multiple datasets found that dolichyl‐phosphate mannosyltransferase subunit 2 (DPM2) is an unfavorable prognostic marker, suggesting its oncogenic role. Cell counting kit‐… Show more
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