2013
DOI: 10.1111/appy.12069
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Depression in male patients on methadone maintenance therapy

Abstract: Introduction: Depression is one of the most common psychiatric conditions in men. The aim of the study was to determine the depressive symptoms and associated factors among men on methadone maintenance therapy (MMT). Methods: A cross-sectional study was conducted involving 108 subjects who attended the Drug Clinic at Hospital Kuala Lumpur. The instruments used include the Structured Clinical Interview for Diagnostic and Statistical Manual, Fourth Edition Axis-I Disorder, Beck Depression Inventory and the 15-it… Show more

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Cited by 20 publications
(17 citation statements)
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“…Numbers of factors such as methadone dosage, methadone duration, age group of the patients, time of assessment, depression, and definition of sexual dysfunction were different across the studies. Such factors could have been the confounding factors that affected the prevalence rate [42][43][44]. Furthermore, studies that were reviewed were of variable quality, and seven of them were rated as having medium-to-high risk of bias (Table 3).…”
Section: Comparison Of Prevalence Ratesmentioning
confidence: 99%
“…Numbers of factors such as methadone dosage, methadone duration, age group of the patients, time of assessment, depression, and definition of sexual dysfunction were different across the studies. Such factors could have been the confounding factors that affected the prevalence rate [42][43][44]. Furthermore, studies that were reviewed were of variable quality, and seven of them were rated as having medium-to-high risk of bias (Table 3).…”
Section: Comparison Of Prevalence Ratesmentioning
confidence: 99%
“…Few such studies have been conducted among MMT users (Madden, Lea, Bath, & Winstock, 2008) and none have been conducted in China. Other factors of depression among MMT users include education, employment status, social support, and family relationships (Baharudin, Mislan, Ibrahim, Sidi, & Nik Jaafar, 2013; Nyamathi et al, 2012; Wang et al, 2012; Weissman, Slobetz, Prusoff, Mezritz, & Howard, 1976). Such factors were also associated with suicidal ideation as depression is a strong predictor of suicidal ideation (Britton & Conner, 2010).…”
Section: Introductionmentioning
confidence: 99%
“…Fifty percent of those on methadone maintenance therapy were found to be suffering from depression 12 . It may be a driving force in motivating opiate-dependent individuals seek treatment 13 , particularly as depression is one of the prime causes of drug addiction relapse 14 . Some antidepressants like Sertraline 15 and Venlafaxine 16 and substances with antidepressant activity such as Berberine 17 and Saffron extract 18 are effective in delaying or reducing addiction relapse irrespective of methadone administration.…”
Section: Introductionmentioning
confidence: 99%