<scp>COVID</scp>‐19 and <scp>ABO</scp> blood groups

Dzik, Sunny; Eliason, Kent; Morris, Edward; Kaufman, Richard M.; North, Crystal M.

doi:10.1111/trf.15946

Cited by 85 publications

(48 citation statements)

References 8 publications

(6 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Most studies that found associations between ABO blood groups and susceptibility to Covid-19, including GWAS studies with large cohorts of patients and controls, reported that individuals with blood group O had a significantly lower risk of SARS-CoV-2 infection ( Ellinghaus et al, 2020 , Shelton et al, 2020 , Valenti et al, 2020 ). However, some studies failed to observe a significant protective effect of blood group for reasons that are yet to be understood ( Boudin et al, 2020 , Dzik et al, 2020 ). More variability in different infection rates across studies occurred for individuals with A, B, and AB blood types.…”

Section: Discussionmentioning

confidence: 99%

“…Studies from China and other parts of the world (USA, Turkey, Europe, Middle Eastern countries) have reported a relationship between the ABO blood group and the susceptibility to Covid-19. Despite some discrepancies, they showed a general trend that the risk of developing a SARS-CoV-2 infection was higher for individuals with type A blood and lower for those with type O blood ( Abdollahi et al, 2020 , Aljanobi et al, 2020 , Boudin et al, 2020 , Dzik et al, 2020 , Ellinghaus et al, 2020 , Gallian et al, 2020 , Göker et al, 2020 , Latz et al, 2020 , Leaf et al, 2020 , Li et al, 2020 , Shelton et al, 2020 , Valenti et al, 2020 , Wu et al, 2020 , Zeng et al, 2020 , Zhao et al, 2020 , Zietz et al, 2020 ). A similar lower risk for blood group O individuals had previously been observed in Hong Kong during the first major SARS outbreak, in 2003 ( Cheng et al, 2005 ).…”

Section: Introductionmentioning

confidence: 98%

See 1 more Smart Citation

Covid-19 and blood groups: ABO antibody levels may also matter

Deleers¹,

Breiman²,

Daubie³

et al. 2021

International Journal of Infectious Diseases

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 98%

Covid-19 and blood groups: ABO antibody levels may also matter

Deleers¹,

Breiman²,

Daubie³

et al. 2021

International Journal of Infectious Diseases

View full text Add to dashboard Cite

“…Based on this review, we excluded ten full-text articles for not meeting our inclusion criteria. A total of seven studies were included in the qualitative synthesis and meta-analysis [16][17][18][19][20][21][22] The flow diagram of the systematic literature review can be found in Fig 1.…”

Section: Study Screeningmentioning

confidence: 99%

The association between ABO blood group and SARS-CoV-2 infection: A meta-analysis

et al. 2020

View full text Add to dashboard Cite

At present, existing evidence about the association between SARS-CoV-2 infection and ABO blood group polymorphism is preliminary and controversial. In this meta-analysis we investigate this association and determine SARS-CoV-2 positive individuals' odds of having a specific blood group compared to controls. We performed a systematic search on MED-LINE and LitCovid databases for studies published through July 15, 2020. Seven studies met inclusion criteria for meta-analysis, including a total of 13 subgroups of populations (7503 SARS-CoV-2 positive cases and 2962160 controls). We analysed the odds of having each blood group among SARS-CoV-2 positive patients compared with controls. Randomeffects models were used to obtain the overall pooled odds ratio (OR). Subgroup and sensitivity analyses were performed in order to explore the source of heterogeneity and results consistency. The results of our meta-analysis indicate that SARS-CoV-2 positive individuals are more likely to have blood group A (pooled OR 1.23, 95%CI: 1.09-1.40) and less likely to have blood group O (pooled OR = 0.77, 95%CI: 0.67-0.88). Further studies are needed to investigate the mechanisms at the basis of this association, which may affect the kinetics of the pandemic according to the blood group distribution within the population.

show abstract

“…A total of seven studies were included in the qualitative synthesis and meta-analysis. [16][17][18][19][20][21][22] The flow diagram of the systematic literature review can be found in…”

Section: Study Screeningmentioning

confidence: 99%

The association between ABO blood group and SARS-CoV-2 infection: a meta-analysis

Golinelli

Boetto

Maietti

et al. 2020

Preprint

View full text Add to dashboard Cite

At present, existing evidence about the association between SARS-CoV-2 infection and ABO blood group polymorphism is preliminary and controversial. In this meta-analysis we investigate this association and determine SARS-CoV-2 positive individuals odds of having a specific blood group compared to controls. We performed a systematic search on MEDLINE and LitCovid databases for studies published through July 12, 2020. 7 studies met inclusion criteria for meta-analysis, including a total of 13 subgroups of populations (7524 SARS-CoV-2 positive cases and 2962160 controls). We analysed the odds of having each blood group among SARS-CoV-2 positive patients compared with controls. Random-effects models were used to obtain the overall pooled odds ratio (OR). Subgroup and sensitivity analyses were performed in order to explore the source of heterogeneity and results consistency. The results of our meta-analysis indicate that SARS-CoV-2 positive individuals are more likely to have blood group A (pooled OR 1.21; 95%CI: 1.08-1.37) and less likely to have blood group O (pooled OR 0.76, 95%CI: 0.66-0.87). Further studies are needed to investigate the mechanisms at the basis of this association, which may affect the kinetics of the pandemic according to the blood group distribution within the population.

show abstract

COVID‐19 and ABO blood groups

Cited by 85 publications

References 8 publications

Covid-19 and blood groups: ABO antibody levels may also matter

Covid-19 and blood groups: ABO antibody levels may also matter

The association between ABO blood group and SARS-CoV-2 infection: A meta-analysis

The association between ABO blood group and SARS-CoV-2 infection: a meta-analysis

Contact Info

Product

Resources

About