ACE2 and TAS2R38 receptor expression in pediatric and adult patients in the nasal and oral cavity
Zechariah G. Franks,
Kavitha Nandakumar,
Lakshmi Santhanam
et al.
Abstract:ObjectiveTo investigate differences in angiotensin‐converting‐enzyme‐2 (ACE2) and bitter taste receptor (TAS2R38) expression between patient age groups and comorbidities to characterize the pathophysiology of coronavirus 19(COVID‐19) pandemic. ACE2 is the receptor implicated to facilitate SARS‐CoV‐2 infections and levels of expression may correlate to the severity of COVID‐19 infection. TAS2R38 has many non‐gustatory roles in disease, with some evidence of severe COVID‐19 disease in certain receptor phenotypes… Show more
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