AARS2 as a novel biomarker for prognosis and its molecular characterization in pan‐cancer
Long Liu,
Jie Gao,
Xudong Liu
et al.
Abstract:IntroductionThe mitochondrial alanyl‐tRNA synthetase 2 (AARS2) as one of aminoacyl‐tRNA synthases (ARSs) performs amino acid transportation and involves protein synthesis. However, its role in cancer remains largely unexplored.MethodsIn this study, more than 10,000 samples were enrolled to explore genomic alterations, biological function, prognosis, and clinical treatment based on AARS2 across pan‐cancer. The molecular characterization of AARS2 was confirmed in hepatocellular carcinoma (HCC) using proteomics a… Show more
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