Sclerotherapy for the management of rectal prolapse in children

Dolejs, Scott C.; Sheplock, Justin; Vandewalle, Robert J.; Landman, Mathew P.; Rescorla, Frederick J.

doi:10.1016/j.jpedsurg.2017.10.015

Cited by 7 publications

(9 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The qualitative analysis of these 16 articles was performed and no articles were excluded. Therefore, only 16 studies were included in this meta-analysis ( 1 , 4 , 5 , 10 – 22 ). The flow diagram was presented according to the PRISMA guideline ( Figure 1 ).…”

Section: Resultsmentioning

confidence: 99%

“…The inclusion criteria of this study were as follows: ( 1 ) Sclerotherapy treatment for pediatric patients with rectal prolapse; ( 2 ) The studies with sclerotherapy outcome and related clinical profiles; ( 3 ) The studies with detailed data of sclerotherapy and pediatric rectal prolapse; ( 4 ) These studies were also published in English language in the journals of science citation index database; and ( 5 ) Retrospective or prospective study. The exclusion criteria were the following: ( 1 ) Some parts of detailed data were unavailable in the content of the articles (unavailable even after inquiring the corresponding authors about the data needed for this meta-analysis); ( 2 ) The authors did not respond or could not have access to the dataset, in which case the articles would be excluded as the category without detailed data; ( 3 ) The studies that do not belong to patients with rectal prolapse or sclerotherapy; and ( 4 ) Review articles.…”

Section: Methodsmentioning

confidence: 99%

“…The qualitative analysis of these 16 articles was performed and no articles were excluded. Therefore, only 16 studies were included in this meta-analysis (1,4,5,(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22). The flow diagram was FIGURE 1 | The preferred reporting items for systematic reviews and meta-analyses (PRISMA) flow diagram of the current meta-analysis.…”

Section: Description Of Studiesmentioning

confidence: 99%

“…The incidence rate of pediatric rectal prolapse was still not clear ( 4 , 5 ). Spontaneous resolution would be around 60–90% in pediatric rectal prolapse.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

The Remission Effects of First Injection of Sclerotherapy for Pediatric Rectal Prolapse: A Systematic Review and Meta-Analysis

Zhou

Shi

Zhang³

et al. 2022

Front. Surg.

View full text Add to dashboard Cite

BackgroundPediatric rectal prolapse is a common issue in clinical practice. Among various managements, sclerotherapy is an important method to successfully treat pediatric rectal prolapse, especially for the first injection. The knowledge of the first injection of sclerotherapy can be revealed by a systemic review and meta-analysis of randomized clinical trials.MethodsWe performed a systematic search and a meta-analysis for the retrospective clinical studies of sclerotherapy in pediatric rectal prolapse. The comparison between remission and recurrence after the first injection of sclerotherapy was performed to find if the first injection of sclerotherapy can treat rectal prolapse completely. After a restricted selection, 17 studies involving 1,091 pediatric rectal prolapse subjects with sclerotherapy were enrolled in a variety of classifications of injection agents. The focused outcome was to check whether the first injection of sclerotherapy can achieve a remission status. The meta-analysis was performed by Review Manager 5.4.ResultsAmong the subjects receiving sclerotherapy, the meta-analysis favors the remission status after receiving the first injection of sclerotherapy. The meta-analysis results showed significant remission tests for the overall effect and significant heterogeneities in odds ratio and the fixed-effects model. The significant therapeutic effects remained, however, even after testing in the relative risk and the random-effects model.ConclusionsDespite significant heterogeneity and relatively low quality of evidence, the first injection of sclerotherapy may conceivably demonstrate therapeutic effects to help the patients of pediatric rectal prolapse achieve a remission status.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Description Of Studiesmentioning

confidence: 99%

“…The incidence rate of pediatric rectal prolapse was still not clear ( 4 , 5 ). Spontaneous resolution would be around 60–90% in pediatric rectal prolapse.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

The Remission Effects of First Injection of Sclerotherapy for Pediatric Rectal Prolapse: A Systematic Review and Meta-Analysis

Zhou

Shi

Zhang³

et al. 2022

Front. Surg.

View full text Add to dashboard Cite

show abstract

“…[6][7][8] The difference is especially true in children less than 4 years of age who are otherwise healthy. 2,6,9 Given the high rate of resolution, the number of children who ultimately undergo surgical intervention is low.…”

Section: Introductionmentioning

confidence: 99%

Surgical Management of Rectal Prolapse in Infants and Children

2020

View full text Add to dashboard Cite

The surgical management of children with rectal prolapse is wide ranging and without consensus within the pediatric surgical community. While the majority of rectal prolapse in infants and children resolves spontaneously or with the medical management of constipation, a small but significant subset of patients may require intervention for persistent symptoms. In this review, we discuss the etiology and pathophysiology of rectal prolapse in both infants and children, options for medical management, described interventions and surgical options and their outcomes, and future avenues for research and investigation.

show abstract