Sclerotherapy for cervical cystic lymphatic malformations in children. Our experience with computed tomography-guided 98% sterile ethanol insertion and a review of the literature

Impellizzeri, Pietro; Romeo, Carmelo; Borruto, Francesca Astra; Granata, Francesca; Scalfari, Gianfranco; Ponte, Francesco Saverio De; Longo, Marcello

doi:10.1016/j.jpedsurg.2010.07.023

Cited by 46 publications

(44 citation statements)

References 28 publications

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“…They are more difficult to resect en bloc [3 && ]. Sclerosants used include doxycycline, bleomycin [46], alcohol [47] and OK-432 [25 && ,48,49]. In-utero sclerosing of a lymphatic malformation has been suggested [50] but is not commonly practiced.…”

Section: Postnatal Managementmentioning

confidence: 99%

EXIT procedure for fetal neck masses

Olutoye¹,

Olutoye²

2012

Current Opinion in Pediatrics

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Section: Postnatal Managementmentioning

confidence: 99%

EXIT procedure for fetal neck masses

Olutoye¹,

Olutoye²

2012

Current Opinion in Pediatrics

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“…OK-432 causes inflammation of the cyst wall and stimulates the immunocyte secretion of a variety of cytokines, including interleukin-6, tumor-necrosis factor, and interferon gamma, which increases the permeability of the endothelium and induces the apoptosis of the lymphatic endothelium, facilitating the excretion of the lesion into the lymphatic vessels and resulting in a contraction of the cyst. The agent also promotes cyst contraction by activating natural killer cells and recruiting T-lymphocytes [1,3,8]. …”

Section: Sclerosing Agentsmentioning

confidence: 99%

“…The skin test for penicillin G allergy should be performed before OK-432 sclerotherapy [8]. OK-432 sclerotherapy may initially be associated with minor inflammatory responses such as swelling, erythema, pain, and mild fever for up to 5 days in many cases, and it is rarely associated with major side effects such as dyspnea and cellulitis [6].…”

Section: Sclerosing Agentsmentioning

confidence: 99%

Ultrasound-guided sclerotherapy for benign non-thyroid cystic mass in the neck

Kim

2014

Ultrasonography

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Surgical excision has traditionally been the treatment of choice for benign non-thyroid cystic neck masses, including lymphatic malformation, ranula, branchial cleft cyst, thyroglossal duct cyst, and parathyroid cyst. However, there is a tendency toward recurrence after surgery, and surgery may be accompanied by complications, including nerve injuries, vascular injuries, and scar formation. Ultrasound-guided sclerotherapy using various agents has been challenged and successfully applied as an alternative treatment for benign non-thyroid cystic neck masses. This report reviews the available sclerosing agents and describes the applications of sclerotherapy to the treatment of benign cystic masses in the neck.

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“…80,81 Sclerotherapy is usually performed through ultrasound-guided puncture and fluoroscopic contrastographic control of the cyst, followed by endocytic injection of sclerosing agents. Literature 82 reports experiences of CT-guided and CT-controlled sclerotherapy. The choice of the sclerosing agent has been a main topic of research and testing in terms of the risk-to-benefit ratio.…”

Section: Osteoid Osteomamentioning

confidence: 99%

Paediatric musculoskeletal interventional radiology

Natali¹,

Paolantonio²,

Fruhwirth³

et al. 2016

BJR

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Interventional radiology technique is now well established and widely used in the adult population. Through minimally invasive procedures, it increasingly replaces surgical interventions that involve higher percentages of invasiveness and, consequently, of morbidity and mortality. For these advantageous reasons, interventional radiology in recent years has spread to the paediatric age as well. The aim of this study was to review the literature on the development, use and perspectives of these procedures in the paediatric musculoskeletal field. Several topics are covered: osteomuscle neoplastic malignant and benign pathologies treated with invasive diagnostic and/or therapeutic procedures such as radiofrequency ablation in the osteoid osteoma; invasive and non-invasive procedures in vascular malformations; treatment of aneurysmal bone cysts; and role of interventional radiology in paediatric inflammatory and rheumatic inflammations. The positive results that have been generated with interventional radiology procedures in the paediatric field highly encourage both the development of new ad hoc materials, obviously adapted to young patients, as well as the improvement of such techniques, in consideration of the fact that childrens' pathologies do not always correspond to those of adults. In conclusion, as these interventional procedures have proven to be less invasive, with lower morbidity and mortality rates as well, they are becoming a viable and valid alternative to surgery in the paediatric population. MUSCULOSKELETAL MALIGNANT TUMOURSOsteosarcoma, Ewing sarcoma and rhabdomyosarcoma are the most common musculoskeletal tumours of childhood and adolescence.

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Sclerotherapy for cervical cystic lymphatic malformations in children. Our experience with computed tomography-guided 98% sterile ethanol insertion and a review of the literature

Cited by 46 publications

References 28 publications

EXIT procedure for fetal neck masses

EXIT procedure for fetal neck masses

Ultrasound-guided sclerotherapy for benign non-thyroid cystic mass in the neck

Paediatric musculoskeletal interventional radiology

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