Sclerosing mesenteritis mimics gynecologic malignancy

Tierney, Christina; Dinkelspiel, Helen E.; Bass, Anne R.; Cimic, Adela; Katzen, Janine; Holcomb, Kevin

doi:10.1016/j.gore.2015.02.005

Cited by 1 publication

(3 citation statements)

References 9 publications

(16 reference statements)

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“…Sclerosing mesenteritis is an inflammatory process within the mesentery and can be categorized into the following three subgroups, depending on the predominant tissue component: mesenteric panniculitis, which is characterized by chronic inflammation; mesenteric lipodystrophy, which is characterized by fat necrosis; and retractile mesenteritis, which is characterized by fibrosis [ 2 , 8 , 10 ]. Distinguishing sclerosing mesenteritis from neoplasms is sometimes difficult because the disease can mimic lymphoma and digestive or gynecologic organ malignancies both clinically and radiographically [ 3 , 6 , 7 ]. Sclerosing mesenteritis remains asymptomatic in 30–50% of cases [ 1 , 10 ].…”

Section: Discussionmentioning

confidence: 99%

“…The prognosis of sclerosing mesenteritis is generally regarded as favorable with supportive treatment [ 1 , 6 , 7 , 12 ]. In spite of having clinical and radiographic findings similar to those of malignancies, sclerosing mesenteritis is treated differently than malignancies.…”

Section: Discussionmentioning

confidence: 99%

“…Although the exact etiology of sclerosing mesenteritis has not been elucidated [ 1 – 6 , 9 – 14 ], it has been reported that the possible risk factors for the disease include malignancy, autoimmune disease, infection, ischemia, trauma, and a history of previous surgery [ 3 , 5 , 8 , 11 , 12 ]. Sclerosing mesenteritis is sometimes indistinguishable from neoplasms because its manifestations and radiographic findings may be identical to those of malignancies [ 3 , 6 , 7 ]. Despite these similarities, sclerosing mesenteritis is treated very differently than malignancies; thus, it is very important that sclerosing mesenteritis is diagnosed correctly so that the disease can be managed adequately.…”

Section: Introductionmentioning

confidence: 99%

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Sclerosing mesenteritis mimicking metachronous peritoneal metastases from descending colon adenocarcinoma

et al. 2017

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BackgroundSclerosing mesenteritis is a non-neoplastic inflammatory disease that occurs in the bowel mesentery. Distinguishing sclerosing mesenteritis from neoplasms may be difficult because of the clinical and radiographic similarities between the two disease entities.Case presentationWe report a case of sclerosing mesenteritis mimicking peritoneal metastases of colorectal carcinoma. A 73-year-old man with stage II descending colon adenocarcinoma with poor prognostic features was found to have developed left lower abdominal quadrant masses on computed tomography (CT) 9 months after undergoing radical surgery. These masses were diagnosed as peritoneal metastases because they grew in size and displayed fluorodeoxyglucose (FDG) uptake 3 months later; thus, a laparotomy was performed. The masses, which were localized in the jejunal mesentery, were excised completely via segmental jejunal resection. Histopathological analysis confirmed that the masses were sclerosing mesenteritis. The patient showed no signs of sclerosing mesenteritis or colorectal carcinoma recurrence during follow-up.ConclusionsIn patients suspected of having localized peritoneal metastasis from malignancies, any masses must be sampled by surgical excisional biopsy and subsequently examined to rule out alternative diagnoses, such as sclerosing mesenteritis.

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