Sclerosing angiomatoid nodular transformation of spleen: an uncommon benign lesion of spleen

Abstract

SANT (sclerosing angiomatoid nodular transformation) is a rare benign vascular tumour of spleen. SANT can mimic benign and malignant conditions of spleen. There are no definite radiological features. It has characteristic histopathology and immunohistochemistry findings which help us to differentiate it from other angiomatoid and tumor-like lesions. Splenectomy is the treatment of choice as it is diagnostic and therapeutic at the same time. We present a case of 22 years female with left upper quadrant pain since, 2 months. Magnetic Resonance Imaging revealed well-defined hypodense mass measuring 6.3×6.1×5.8cm in the spleen, with provisional diagnosis of hemangioma. Laproscopic splenectomy was done and a diagnosis of SANT was made on histology and immunohistochemistry. This case shows us that SANT should be considered in the differential diagnosis of splenic solid lesions.