Sclérodermie systémique

Hachulla, É.; Launay, David

doi:10.1016/j.emcrho.2005.07.001

Cited by 5 publications

(3 citation statements)

References 68 publications

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“…Des AANuc existent chez 20 à 30 % des ScS [6]. L'état d'activité des patients et la réponse au traitement sont sans influence sur la positivité et le titre des AANuc.…”

Section: Auto-anticorps Anti-nucléolaires Prévalence Et Spécificitéunclassified

Quel est l’intérêt de la recherche des anticorps anti-nucléolaires dans la sclérodermie systémique ?

Comacle

Padelli

Renaudineau

et al. 2011

Immuno-analyse & Biologie Spécialisée

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“…Des AANuc existent chez 20 à 30 % des ScS [6]. L'état d'activité des patients et la réponse au traitement sont sans influence sur la positivité et le titre des AANuc.…”

Section: Auto-anticorps Anti-nucléolaires Prévalence Et Spécificitéunclassified

Quel est l’intérêt de la recherche des anticorps anti-nucléolaires dans la sclérodermie systémique ?

Comacle

Padelli

Renaudineau

et al. 2011

Immuno-analyse & Biologie Spécialisée

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“…SSc patients can present with internal organ involvement. 2 Skin involvement is assessed by the modified Rodnan skin score (mRSS), which reflects the severity of the disease. 3 Skin involvement is also represented by Raynaud's phenomenon, 2 sclerodactyly, telangiectasia, 4 calcinosis, 5 or pigmentation disorders.…”

Section: Introductionmentioning

confidence: 99%

“…2 Skin involvement is assessed by the modified Rodnan skin score (mRSS), which reflects the severity of the disease. 3 Skin involvement is also represented by Raynaud's phenomenon, 2 sclerodactyly, telangiectasia, 4 calcinosis, 5 or pigmentation disorders. 6 Facial involvement is characterized by a possible loss of expression lines, the loss of the nasolabial fold, and the accentuation of perioral wrinkles, as well as wasting of the temporal and neck muscles.…”

Section: Introductionmentioning

confidence: 99%

Perception of aesthetic impairment in patients with systemic sclerosis determined using a semi-quantitative scale and its association with disease characteristics

Farhat,

Guerreschi,

Morell-Dubois

et al. 2024

Journal of Scleroderma and Related Disorders

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Background: Systemic sclerosis is a fibrotic disease. Body image assessments could be key in optimizing care; however, data are scarce. The main objective was to assess the perception of aesthetic impairment using a visual aesthetic evaluation scale in patients with systemic sclerosis compared with healthy subjects. The secondary objectives were to assess associations between the perception of aesthetic impairment and scores on standardized questionnaires for aesthetic impairment as well as clinical, psychological/quality of life, and functional parameters of patients with systemic sclerosis. Methods: This study evaluated and compared the perception of aesthetic impairment in two populations: patients with systemic sclerosis from a referral center at Lille Hospital, France, and healthy controls. Results: This study included 88 patients (69 (78.4%) women) with a median age of 52 years and 88 controls (49 (55.7%) women) with a median age of 45 years. The perception of aesthetic impairment assessed using the aesthetic evaluation scale was poorer in systemic sclerosis patients than in controls (3.7 ± 0.3 vs 2.8 ± 0.3, p = 0.028) and was statistically correlated with assessments using the adapted satisfaction with appearance, a specific aesthetic impact assessment questionnaire for patients with systemic sclerosis. Patients with anxiety or depressive symptoms had significantly higher aesthetic evaluation scale scores. Systemic sclerosis patients with facial involvement and pitting scars had a worse perception of aesthetic impairment. Compared with healthy controls, systemic sclerosis patients had a worse perception of aesthetic impairment, especially systemic sclerosis patients with anxiety or depression and those with facial and hand involvement. Conclusion: The aesthetic evaluation scale appears to be an easy-to-use tool to evaluate body image. Correlations of the aesthetic evaluation scale score with psychological and quality of life parameters reflect the importance of these parameters for body image evaluation and its complex assessment. Trial registration: Clinical Trial NCT03271320 (Registered 9 January 2017, https://www.clinicaltrials.gov/ct2/show/NCT03271320?term=NCT03271320&cntry=FR&draw=2&rank=1 ).

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